Eilyn R. Lacy

Johnson & Johnson (United States) — United States

Medicine · Health Sciences

23h-index2.2kcitations46works5.32yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Monoclonal and Polyclonal Antibodies Research(22), Glycosylation and Glycoproteins Research(11), Protein purification and stability(9), T-cell and B-cell Immunology(5), Psoriasis: Treatment and Pathogenesis(5)

Publications46 total

Guselkumab binding to CD64+ IL-23–producing myeloid cells enhances potency for neutralizing IL-23 signaling
Frontiers in Immunology·2025· 19 citedOpen Access
A novel label-free method to determine equilibrium dissociation constants of antibodies binding to cell surface proteins
Scientific Reports·2025· 1 citedOpen Access
S1241 Guselkumab Binding to CD64+ IL-23–Producing Myeloid Cells Enhances Potency for Neutralizing IL-23 Signaling
The American Journal of Gastroenterology·2024
Abstract LB122: JNJ-87890387, a novel ENPP3 bispecific T-cell redirector (ENPP3xCD3) with tumor selectivity through targeting apical surface antigens
Cancer Research·2024· 1 cited
43272 Differentiation of Therapeutic Monoclonal Antibodies Targeting IL-23 for the Treatment of Psoriatic Disease
Journal of the American Academy of Dermatology·2023Open Access
769 GUSELKUMAB, AN IL-23P19 SUBUNIT-SPECIFIC MONOCLONAL ANTIBODY, BINDS CD64+ MYELOID CELLS AND POTENTLY NEUTRALIZES IL-23 PRODUCED FROM THE SAME CELLS
Gastroenterology·2023· 1 citedOpen Access
Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections
Cell Host & Microbe·2023· 23 cited
“Stapling” scFv for multispecific biotherapeutics of superior properties
mAbs·2023· 25 citedOpen Access
Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis
Med·2022· 70 cited
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody
Journal of Alzheimer s Disease·2020· 22 cited
Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor
Journal of Pharmacology and Experimental Therapeutics·2019· 2 citedOpen Access
Abstract 4818: Fc-mediated mechanism of action for the novel EGFR-cMET bispecific antibody (JNJ-61186372) in non-small cell lung cancer
Cancer Research·2019
Abstract 4818: Fc-mediated mechanism of action for the novel EGFR-cMET bispecific antibody (JNJ-61186372) in non-small cell lung cancer
Experimental and Molecular Therapeutics·2019
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo
Journal of Alzheimer s Disease·2018· 40 citedOpen Access
Abstract 3813: Development of JNJ-64164711, a low fucose anti-GITR antibody for enhanced depletion of tumor regulatory T cells (Tregs)
Cancer Research·2018
Human IgG subclass cross-species reactivity to mouse and cynomolgus monkey Fcγ receptors
Immunology Letters·2018· 28 cited
Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody
Molecular Metabolism·2018· 16 citedOpen Access
Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance
Diabetes·2016· 13 citedOpen Access
Monoclonal antibodies targeting ST2L Domain 1 or Domain 3 differentially modulate IL-33-induced cytokine release by human mast cell and basophilic cell lines
Molecular Immunology·2016· 8 cited
Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti‐tau antibody AT8
Proteins Structure Function and Bioinformatics·2016· 125 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Sheng‐Jiun Wu(10), Rupesh Nanjunda(10), Jinquan Luo(8), A. Teplyakov(8), Richard W. Kriwacki(5), Gary L. Gilliland(5), T. Malia(5), Ken Boakye(4), Sheri L. Moores(4), Mark L. Chiu(4), Kacey L. Sachen(4), Phuc Bao(4), Anne M. Fourie(4), Gabriela Canziani(3), Yiqing Feng(3), Robin Ernst(3), Marc Vandermeeren(3), Marc Mercken(3), Steven Jacobs(3), Kristof Van Kolen(3)