Devapregasan Moodley

Medicine · Health Sciences

13h-index898citations28works15.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(5), Immune Cell Function and Interaction(4), Cancer Immunotherapy and Biomarkers(3), Tuberculosis Research and Epidemiology(2), Rheumatoid Arthritis Research and Therapies(2)

Publications27 total

Endogenous IL-27 during toxoplasmosis limits early monocyte responses and their inflammatory activation by pathological T cells
mBio·2024· 15 citedOpen Access
674 IL-27 signaling drives a type 1 interferon-like gene expression program of immunoregulatory pathways associated with cancer progression
Regular and Young Investigator Award Abstracts·2021· 1 citedOpen Access
Abstract 1607: IL-27 signaling serves as an immunological checkpoint for NK cells to promote hepatocellular carcinoma in multiple murine models
Immunology·2021
Abstract 1802: CD39 inhibition shapes the transcriptional landscape of myeloid cells and induces proinflammatory states in the CT26 syngeneic tumor model
Cancer Research·2021· 2 cited
727 Increased serum levels of EBI3 are associated with poor outcome in hepatocellular carcinoma patients and SRF388, a first-in-class IL-27 blocking antibody, inhibits the growth of murine liver tumors
Regular and Young Investigator Award Abstracts·2020· 1 citedOpen Access
Abstract 4550: Increased IL-27 is associated with poor prognosis in renal cell carcinoma and supports use of SRF388, a first-in-class IL-27p28 blocking antibody, to counteract IL-27-mediated immunosuppression in this setting
Cancer Research·2020· 10 cited
Abstract 558: MERTK-specific antibodies that have therapeutic antitumor activity in mice disrupt the integrity of the retinal pigmented epithelium in cynomolgus monkeys
Cancer Research·2019· 8 cited
Abstract 558: MERTK-specific antibodies that have therapeutic antitumor activity in mice disrupt the integrity of the retinal pigmented epithelium in cynomolgus monkeys
Immunology·2019· 1 cited
IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors
ImmunoHorizons·2019· 77 citedOpen Access
Sirtuin 1 rs1467568 and rs7895833 in South African Indians with early-onset coronary artery disease
Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa·2016· 19 citedOpen Access
Network pharmacology of JAK inhibitors
Proceedings of the National Academy of Sciences·2016· 64 citedOpen Access
The Arg72 variant of the p53 functional polymorphism (rs1042522) is associated with coronary artery disease in young South Africans of Indian ancestry
Gene·2016· 12 cited
TB/HIV pleurisy reduces Th17 lymphocyte proportion independent of the cytokine microenvironment
Tuberculosis·2016· 4 cited
Mycobacterium tuberculosis: Manipulator of Protective Immunity
International Journal of Molecular Sciences·2016· 78 citedOpen Access
Parsing the Interferon Transcriptional Network and Its Disease Associations
Cell·2016· 336 cited
Parsing the Interferon Transcriptional Network and Its Disease Associations
DSpace@MIT (Massachusetts Institute of Technology)·2016Open Access
Increased SIRT3 Expression and Antioxidant Defense under Hyperglycemic Conditions in HepG2 Cells
Metabolic Syndrome and Related Disorders·2015· 21 cited
Methylenetetrahydrofolate reductase C677T polymorphism is associated with increased risk of coronary artery disease in young South African Indians
Gene·2015· 23 cited
Atorvastatin Increases miR‐124a Expression: A Mechanism of Gamt Modulation in Liver Cells
Journal of Cellular Biochemistry·2015· 13 cited
Fumonisin B1 inhibits apoptosis in HepG2 cells by inducing Birc-8/ILP-2
Toxicology Letters·2015· 28 cited
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Frequent Co-authors

Anil A. Chuturgoon(14), Alisa Phulukdaree(12), Jonathan A. Hill(8), Matthew Rausch(7), Pamela M. Holland(7), Kerry White(6), Jing Hua(6), Sajidah Khan(5), Vito J. Palombella(5), Benjamin H. Lee(4), Ricard Masia(4), Secil Koseoglu(4), Sara Mostafavi(3), Hideyuki Yoshida(3), James D. Clark(3), Martin Hegen(3), Jean‐Baptiste Telliez(3), Diane Mathis(3), Christophe Benoıst(3), Prithiksha Ramkaran(3)