Angelika Caputo

Novartis (Switzerland) — Switzerland

Arts and Humanities · Social Sciences

15h-index2.4kcitations132works6.02yr avg
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Research Topics

Sports Science and Education(23), Alzheimer's disease research and treatments(21), Physics and Engineering Research Articles(16), Cholinesterase and Neurodegenerative Diseases(13), Dementia and Cognitive Impairment Research(12)

Publications132 total

Oral splicing modulator branaplam in Huntington’s disease: a phase 2 randomized controlled trial
Nature Medicine·2026Open Access
Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies
Alzheimer s & Dementia·2024· 12 citedOpen Access
Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired <i>APOE</i> ε4 homozygotes
Alzheimer s & Dementia·2023· 23 citedOpen Access
Rationale for the selection of dual primary endpoints in prevention studies of cognitively unimpaired individuals at genetic risk for developing symptoms of Alzheimer’s disease
Alzheimer s Research & Therapy·2023· 4 citedOpen Access
Rationale for the selection of dual primary endpoints in prevention studies of cognitively unimpaired individuals at genetic risk for developing symptoms of Alzheimer’s disease
Research Square (Research Square)·2022Open Access
API generation program: Active immunotherapy CAD106 slows amyloid deposition in cognitively unimpaired APOE4 homozygotes
Alzheimer s & Dementia·2021· 1 cited
The Generation program: Baseline characteristics of cognitively unimpaired APOE4 carriers recruited for Generation study 1 and Generation study 2
Alzheimer s & Dementia·2020· 2 citedOpen Access
The API Generation program: Umibecestat treatment and discontinuation effects on hippocampal and whole brain volumes in the overall population and amyloid‐negative APOE4 homozygotes
Alzheimer s & Dementia·2020· 6 citedOpen Access
Umibecestat in the API Generation program: Worsening in RBANS and/or CDR on treatment reverses after wash‐out
Alzheimer s & Dementia·2020· 6 cited
The API Generation program: Biomarker phenotyping of cognitively unimpaired participants screened in Generation study 1 and Generation study 2
Alzheimer s & Dementia·2020· 2 cited
Modelling Decline in Cognition to Decline in Function in Alzheimer’s Disease
Current Alzheimer Research·2020· 6 cited
The Alzheimer’s Prevention Initiative Composite Cognitive Test: a practical measure for tracking cognitive decline in preclinical Alzheimer’s disease
Alzheimer s Research & Therapy·2020· 36 citedOpen Access
F2‐03‐04: ASSESSING CLINICAL MEANINGFULNESS OF OUTCOMES IN THE ALZHEIMER'S PREVENTION INITIATIVE GENERATION PROGRAM
Alzheimer s & Dementia·2019Open Access
The Alzheimer Prevention Initiative Generation Program: Evaluation of CNP520 in Preclinical Alzheimer’s Disease (P4.1-005)
Neurology·2019· 2 cited
The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease
Alzheimer s & Dementia Translational Research & Clinical Interventions·2019· 114 citedOpen Access
A Testing Strategy With Adaptive Dose Selection and Two Endpoints
Statistics in Biopharmaceutical Research·2018· 4 citedOpen Access
P4‐014: ESTIMAND IN EARLY ALZHEIMER'S DISEASE: PROGRESS UPDATE FROM THE INTERNATIONAL ALZHEIMER'S DISEASE SCIENTIFIC WORKING GROUP (AD SWG) SUBSTREAM
Alzheimer s & Dementia·2018· 1 cited
O4‐08‐03: PSYCHOSOCIAL OUTCOMES OF APOE E4 GENOTYPE DISCLOSURE IN THE GENERATION STUDY
Alzheimer s & Dementia·2018· 2 citedOpen Access
P2‐036: WHY AND HOW WE THINK THAT CLINICAL TRIALS OF THERAPIES FOR ALZHEIMER'S DISEASE CAN BE SUCCESSFUL: A SIMULATION PLATFORM FOR PRECLINICAL AD
Alzheimer s & Dementia·2018
P1‐071: ESTIMANDS IN PRECLINICAL AD: CASE STUDY IN THE GENERATION PROGRAM
Alzheimer s & Dementia·2018
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Frequent Co-authors

Ana Graf(19), Marie‐Emmanuelle Riviere(18), Pierre N. Tariot(12), Jessica B. Langbaum(12), Eric M. Reiman(10), Fonda Liu(8), Iris Pigeot(8), J. Michael Ryan(7), Marie‐Laure Rouzade‐Dominguez(7), Yihan Sui(7), Pilar Cazorla(7), Vissia Viglietta(6), Javier Ricart(6), Ludwig Fahrmeir(6), Rita Künstler(6), Erika Graf(5), Beth Borowsky(5), Peter Quarg(5), Gϋnter von Minckwitz(4), J. Hilfrich(4)