Patricia E. Cole

Takeda (United States) — United States

Medicine · Health Sciences

42h-index8.1kcitations124works12.32yr avg
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Research Topics

Dementia and Cognitive Impairment Research(14), Health Systems, Economic Evaluations, Quality of Life(11), Radiation Dose and Imaging(11), Alzheimer's disease research and treatments(9), Medical Imaging Techniques and Applications(9)

Publications123 total

Abstract ND09: Actinium-225 -PSMA-Trillium (BAY 3563254): Preclinical evaluation and clinical imaging study of a novel 225Ac-labeled PSMA-targeting small molecule triad for the treatment of mCRPC
Cancer Research·2024
How Can Radiopharmaceutical Therapies Reach Their Full Potential? Improving Dose Reporting and Phase I Clinical Trial Design
Journal of Clinical Oncology·2024· 26 cited
Magnetic Resonance Enterography Assessment of Transmural Healing with Vedolizumab in Moderate to Severe Crohn’s Disease: Feasibility in the VERSIFY Phase 3 Clinical Trial
Clinical and Experimental Gastroenterology·2024· 11 citedOpen Access
Comparison of Cerebral Blood Flow in Regions Relevant to Cognition After Enzalutamide, Darolutamide, and Placebo in Healthy Volunteers: A Randomized Crossover Trial
Targeted Oncology·2023· 24 citedOpen Access
<sup>89</sup>Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted <sup>227</sup>Th-conjugate therapy in mice
Journal of Nuclear Medicine·2022· 6 citedOpen Access
Hypothetical generalized framework for a new imaging endpoint of therapeutic activity in early phase clinical trials in brain tumors
Neuro-Oncology·2022· 22 citedOpen Access
Preclinical characterization of [18F]T-008, a novel PET imaging radioligand for cholesterol 24-hydroxylase
European Journal of Nuclear Medicine and Molecular Imaging·2021· 18 citedOpen Access
<i>In Vitro</i> and <i>In Vivo</i> Comparison of 3,2-HOPO Versus Deferoxamine-Based Chelation of Zirconium-89 to the Antimesothelin Antibody Anetumab
Cancer Biotherapy and Radiopharmaceuticals·2021· 14 citedOpen Access
Radiographic read paradigms and the roles of the central imaging laboratory in neuro-oncology clinical trials
Neuro-Oncology·2020· 17 citedOpen Access
Su1897 TRANSMURAL HEALING WITH VEDOLIZUMAB IN PATIENTS WITH ACTIVE CROHN'S DISEASE
Gastroenterology·2020
Machine learning for comprehensive forecasting of Alzheimer’s Disease progression
Scientific Reports·2019· 207 citedOpen Access
Abstract 1141: Preclinical analysis of biodistribution and PET imaging of a zirconium-89 labeled PSMA-targeted antibody-chelator conjugate
Cancer Research·2019· 3 cited
Abstract 1141: Preclinical analysis of biodistribution and PET imaging of a zirconium-89 labeled PSMA-targeted antibody-chelator conjugate
Tumor Biology·2019Open Access
Evaluation of [18F]MNI-792 as PET tracer for Brain cholesterol 24hydroxylase in Healthy Volunteers
2019
Applications of Neuroimaging Biomarkers in CNS Drug Development
Handbook of behavioral neuroscience·2019
P3‐031: THE CRITICAL PATH FOR ALZHEIMER'S DISEASE: HIPPOCAMPAL VOLUME AS AN ENRICHMENT BIOMARKER IN TRIALS OF PATIENTS WITH MILD COGNITIVE IMPAIRMENT
Alzheimer s & Dementia·2018
Radiation dosimetry and biodistribution of [18F]PF-05270430, a radiotracer for phosphodiesterase 2A (PDE2A) in rhesus macaques and humans
2018
[P4–014]: THE COALITION AGAINST MAJOR DISEASES: TOWARD U.S. FDA QUALIFICATION OF HIPPOCAMPAL VOLUME AS A BIOMARKER FOR ENRICHMENT IN CLINICAL TRIALS FOR PRE‐DEMENTIA STAGES OF ALZHEIMER'S DISEASE
Alzheimer s & Dementia·2017
Repeatability of MR Elastography of Liver: A Meta-Analysis
Radiology·2017· 132 citedOpen Access
The roles of inflammation and immune mechanisms in Alzheimer's disease
Alzheimer s & Dementia Translational Research & Clinical Interventions·2016· 229 citedOpen Access
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Frequent Co-authors

Stanley M. Garn(9), Clifford R. Jack(7), John F. Cardella(7), Adam J. Schwarz(6), David Sacks(6), David Hill(6), Nick C. Fox(5), Curtis A. Lewis(5), Joyce Suhy(4), Alain Drooz(4), Michael W. Weiner(3), Donald L. Miller(3), Stephen Balter(3), Hollington T. Lu(3), Beth A. Schueler(3), Michael Geisinger(3), Alejandro Berenstein(3), Robin Albert(3), Jeffrey D. Georgia(3), Patrick T. Noonan(3)