Adam M. Lopez

The University of Texas Southwestern Medical Center — United States

Medicine · Health Sciences

13h-index479citations31works14.02yr avg
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Research Topics

Lysosomal Storage Disorders Research(14), Sphingolipid Metabolism and Signaling(11), Cholesterol and Lipid Metabolism(10), Gut microbiota and health(4), Carbohydrate Chemistry and Synthesis(4)

Publications31 total

Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism
Nature Metabolism·2024· 28 citedOpen Access
688 COLONIC ENTEROENDOCRINE CELLS CONTROL HOST METABOLISM THROUGH MICROBIAL REGULATION
Gastroenterology·2024
An enteroendocrine-microbial axis in the large intestine controls host metabolism
Research Square (Research Square)·2023Open Access
434: MICROBIOME-PROMOTED HYPERPHAGIA AND OBESITY ARE CONTROLLED BY ENDOCRINE PATHWAYS IN THE COLON
Gastroenterology·2022
Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease
Lipids·2021· 4 citedOpen Access
Paneth cell–derived growth factors support tumorigenesis in the small intestine
Life Science Alliance·2020· 14 citedOpen Access
Regulation of murine copper homeostasis by members of the COMMD protein family
Disease Models & Mechanisms·2020· 39 citedOpen Access
Delineation of metabolic responses of Npc1 mice lacking the cholesterol-esterifying enzyme SOAT2 to acute treatment with 2-hydroxypropyl-β-cyclodextrin
Steroids·2020· 5 citedOpen Access
NK cell defects in X-linked pigmentary reticulate disorder
JCI Insight·2019· 21 citedOpen Access
Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling
Nature Communications·2019· 124 citedOpen Access
Ontogenesis and Modulation of Intestinal Unesterified Cholesterol Sequestration in a Mouse Model of Niemann–Pick C1 Disease
Digestive Diseases and Sciences·2019· 4 cited
Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation
Cell Reports·2018· 16 citedOpen Access
Niemann-Pick C1-deficient mice lacking sterol<i>O</i>-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function
American Journal of Physiology-Gastrointestinal and Liver Physiology·2018· 10 citedOpen Access
Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/<i>Mecp2</i><sup><i>tm1.1Bird</i></sup> Mouse, a Model for Rett Syndrome
Lipids·2018· 10 cited
Impact of loss of SOAT2 function on disease progression in the lysosomal acid lipase-deficient mouse
Steroids·2017· 6 cited
Quantitation of the rates of hepatic and intestinal cholesterol synthesis in lysosomal acid lipase-deficient mice before and during treatment with ezetimibe
Biochemical Pharmacology·2017· 11 citedOpen Access
Measurement of Rates of Cholesterol and Fatty Acid Synthesis In Vivo Using Tritiated Water
Methods in molecular biology·2017· 8 cited
‘Corrigenda to “Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis” [Brain Res. 1654 (2017) 77–84]’
Brain Research·2016· 2 citedOpen Access
Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis
Brain Research·2016· 25 citedOpen Access
PRD125, a Potent and Selective Inhibitor of Sterol O-Acyltransferase 2 Markedly Reduces Hepatic Cholesteryl Ester Accumulation and Improves Liver Function in Lysosomal Acid Lipase-Deficient Mice
Journal of Pharmacology and Experimental Therapeutics·2015· 10 citedOpen Access
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Frequent Co-authors

Stephen D. Turley(21), Kenneth S. Posey(11), Ezra Burstein(9), Charina M. Ramirez(8), Jen-Chieh Chuang(8), Luis Sifuentes-Dominguez(7), Joyce J. Repa(7), Shuai Tan(5), Da Jia(4), Daniel D. Billadeau(4), Jacobo L. Santolaya(4), Gonçalo Vale(4), Amika Singla(3), Teppei Fujikawa(3), Sensen Chi(3), Colin P. Bergstrom(3), Qing Chen(3), Anna M. Taylor(3), Petro Starokadomskyy(3), Ryan Jones(3)