Riccardo Bertini

University of L'Aquila — Italy

Immunology and Microbiology · Life Sciences

37h-index5.4kcitations89works2.02yr avg
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Research Topics

Immune Response and Inflammation(30), Chemokine receptors and signaling(24), Cell Adhesion Molecules Research(12), Inflammatory mediators and NSAID effects(10), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(10)

Publications88 total

The dual non-competitive CXCR1/2 inhibitor ladarixin impairs neutrophil extravasation without altering intravascular adhesion
Haematologica·2025· 2 citedOpen Access
Therapeutic inhibition of CXCR1/2: where do we stand?
Internal and Emergency Medicine·2023· 46 citedOpen Access
Inflammation-Independent Antinociceptive Effects of DF2755A, a CXCR1/2 Selective Inhibitor: A New Potential Therapeutic Treatment for Peripheral Neuropathy Associated to Non-Ulcerative Interstitial Cystitis/Bladder Pain Syndrome
Frontiers in Pharmacology·2022· 7 citedOpen Access
Active surveillance for small renal masses: a prospective translational study update (NCT03804320)
European Urology Open Science·2020Open Access
Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief
Proceedings of the National Academy of Sciences·2014· 77 citedOpen Access
Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non‐competitive allosteric inhibitor
British Journal of Pharmacology·2011· 72 citedOpen Access
Structure–Activity Relationship of novel phenylacetic CXCR1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 6 citedOpen Access
Role of the Chemokine Receptor CXCR2 in Bleomycin-Induced Pulmonary Inflammation and Fibrosis
American Journal of Respiratory Cell and Molecular Biology·2008· 133 cited
The chemokine receptors CXCR1/CXCR2 modulate antigen‐induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature
Arthritis & Rheumatism·2008· 152 citedOpen Access
Allosteric inhibitors of chemoattractant receptors: opportunities and pitfalls
Trends in Pharmacological Sciences·2008· 28 cited
Treatment with DF 2162, a non‐competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice
British Journal of Pharmacology·2008· 97 citedOpen Access
Supplementary Material for: Chemokine MIP-2/CXCL2, Acting on CXCR2, Induces Motor Neuron Death in Primary Cultures
Figshare·2008Open Access
Blockade of the chemokine receptor CXCR2 ameliorates adjuvant‐induced arthritis in rats
British Journal of Pharmacology·2007· 87 citedOpen Access
Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2
Journal of Medicinal Chemistry·2007· 96 cited
Crucial pathophysiological role of CXCR2 in experimental ulcerative colitis in mice
Journal of Leukocyte Biology·2007· 96 cited
Protective Effect of an Inhibitor of Interleukin-8 (Meraxin) From Ischemia and Reperfusion Injury in a Rat Model of Kidney Transplantation
Transplantation Proceedings·2007· 15 cited
Reparixin, an Inhibitor of CXCR2 Function, Attenuates Inflammatory Responses and Promotes Recovery of Function after Traumatic Lesion to the Spinal Cord
Journal of Pharmacology and Experimental Therapeutics·2007· 58 cited
The Interleukin-8 (IL-8/CXCL8) Receptor Inhibitor Reparixin Improves Neurological Deficits and Reduces Long-term Inflammation in Permanent and Transient Cerebral Ischemia in Rats
Molecular Medicine·2007· 86 citedOpen Access
Chemokine MIP-2/CXCL2, Acting on CXCR2, Induces Motor Neuron Death in Primary Cultures
NeuroImmunoModulation·2007· 46 cited
Acknowledgement to the Reviewers
NeuroImmunoModulation·2007Open Access
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Frequent Co-authors

Cinzia Bizzarri(19), Pietro Ghezzi(18), Marcello Allegretti(15), Francesco Colotta(13), Gianfranco Caselli(8), Massimo Locati(8), Pia Villa(7), Mauro Martins Teixeira(7), Alberto Mantovani(6), Maria Neve Cervellera(6), Rosa Di Bitondo(6), Laura Brandolini(6), G. Melillo(6), Alessio Moriconi(5), Emanuela Galliera(5), Barbara Cavalieri(5), Marina Bianchi(5), Andrea R. Beccari(5), Luigi Pellegrini(5), Rita Sergi(4)