Marc Tjwa

Biochemistry, Genetics and Molecular Biology · Life Sciences

43h-index9.3kcitations107works0.02yr avg
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Research Topics

Angiogenesis and VEGF in Cancer(35), Protease and Inhibitor Mechanisms(15), Cancer, Hypoxia, and Metabolism(9), Phagocytosis and Immune Regulation(9), Pregnancy and preeclampsia studies(8)

Publications106 total

A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer
The Oncologist·2023· 1 citedOpen Access
Role of Gas6 in erythropoiesis and anemia in mice
UNC Libraries·2020Open Access
Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1+ Leukemia
Cancer Cell·2020· 5 citedOpen Access
Differentiated pharmacokinetic and pharmacodynamic properties of a highly selective MET kinase inhibitor, OMO-1: Implications for efficacy and safety.
Journal of Clinical Oncology·2019
Modular phase I/II clinical trial evaluating the selective MET-kinase inhibitor OMO-1 in patients with advanced malignancies: Safety and proof of mechanism.
Journal of Clinical Oncology·2019· 1 cited
Deficiency of the T cell regulator <i>Casitas B-cell lymphoma-B</i> aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death
European Heart Journal·2018· 58 citedOpen Access
Decreased microglial numbers in Vav1-Cre + :dicer knock-out mice suggest a second source of microglia beyond yolk sac macrophages
Annals of Anatomy - Anatomischer Anzeiger·2018· 12 cited
Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment
OncoImmunology·2015· 273 citedOpen Access
Supporting Roles of Platelet Thrombospondin-1 and CD36 in Thrombus Formation on Collagen
Arteriosclerosis Thrombosis and Vascular Biology·2014· 74 citedOpen Access
Hypercholesterolemia‐induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis
The FASEB Journal·2014· 110 cited
The role of RNA interference in the developmental separation of blood and lymphatic vasculature
Vascular Cell·2014· 7 citedOpen Access
Diabetes Causes Bone Marrow Autonomic Neuropathy and Impairs Stem Cell Mobilization via Dysregulated <i>p66Shc</i> and <i>Sirt1</i>
Diabetes·2013· 150 citedOpen Access
Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties
Cancer Cell·2013· 146 citedOpen Access
Circulating Apoptotic Endothelial Cells and Apoptotic Endothelial Microparticles Independently Predict the Presence of Cardiac Allograft Vasculopathy
Journal of the American College of Cardiology·2012· 46 cited
Abstract 158: CD40L Regulates Hematopoietic Stem and Progenitor Cell Biology by Inducing Adhesion-Mediated Quiescence
Arteriosclerosis Thrombosis and Vascular Biology·2012· 1 cited
Abstract 11683: Class IIb Histone Deacetylase 6 Regulates Endothelial Cell Migration and Angiogenesis by Deacetylation of Cortactin
Circulation·2011
Prognostic Significance and Target Potential of Axl in Acute Myeloid Leukemia
Blood·2011
PlGF Repairs Myocardial Ischemia through Mechanisms of Angiogenesis, Cardioprotection and Recruitment of Myo-Angiogenic Competent Marrow Progenitors
PLoS ONE·2011· 64 citedOpen Access
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin
The EMBO Journal·2011· 193 cited
Another angiogenesis-independent role for VEGF: SDF1-dependent cardiac repair via cardiac stem cells
Cardiovascular Research·2011· 10 citedOpen Access
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Frequent Co-authors

Peter Carmeliet(32), Mieke Dewerchin(15), Lieve Moons(14), Aernout Luttun(9), Stéphane Plaisance(6), Esther Lutgens(6), Rute Moura(6), Marc Hoylaerts(5), Veerle Compernolle(4), Geert Carmeliet(4), Koen Brusselmans(4), Florea Lupu(4), Karl H. Plate(4), Diether Lambrechts(4), Patrick H. Maxwell(4), Monica Autiero(4), Désiré Collen(4), Ulf Eriksson(4), Andreas M. Zeiher(3), Stefanie Dimmeler(3)