Yungui Zhou

Gladstone Institutes — United States

Medicine · Health Sciences

27h-index6.5kcitations54works4.52yr avg
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Research Topics

Alzheimer's disease research and treatments(25), Neuroinflammation and Neurodegeneration Mechanisms(22), Neurological Disease Mechanisms and Treatments(6), Neurogenesis and neuroplasticity mechanisms(5), Immune cells in cancer(5)

Publications54 total

Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD
Communications Biology·2025· 1 citedOpen Access
Fibrinogen inhibits sonic hedgehog signaling and impairs neonatal cerebellar development after blood–brain barrier disruption
Proceedings of the National Academy of Sciences·2024· 8 citedOpen Access
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
Nature Communications·2022· 286 citedOpen Access
Data from: Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
Zenodo (CERN European Organization for Nuclear Research)·2022· 1 citedOpen Access
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Cell·2022· 299 citedOpen Access
AD-linked R47H-<i>TREM2</i>mutation induces disease-enhancing microglial states via AKT hyperactivation
Science Translational Medicine·2021· 128 citedOpen Access
Tau interactome mapping reveals dynamic processes in synapses and mitochondria associated with neurodegenerative disease
2021· 1 citedOpen Access
BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis
Brain·2021· 30 citedOpen Access
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
2021· 15 citedOpen Access
Preliminary Exploration of the Initial Diagnostic Prediction Model of Moderate Coronavirus Disease 2019 (2019-nCoV) Based on Clinical Data
Open Journal of Nursing·2021Open Access
A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain
eLife·2020· 79 citedOpen Access
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia
Scientific Reports·2020· 18 citedOpen Access
AD-linked R47H- <i>TREM2</i> mutation induces disease-enhancing proinflammatory microglial states in mice and humans
2020· 3 citedOpen Access
Author response: A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain
2020· 2 citedOpen Access
Microglial microRNAs mediate sex-specific responses to tau pathology
Nature Neuroscience·2019· 107 citedOpen Access
A Mac2-positive progenitor-like microglial population survives independent of CSF1R signaling in adult mouse brain
2019· 9 citedOpen Access
P4‐511: A NOVEL ROLE FOR THE FTD‐CAUSING PROTEIN PROGRANULIN IN APOPTOSIS SIGNALING
Alzheimer s & Dementia·2019Open Access
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain
PLoS Biology·2019· 152 citedOpen Access
AD-Linked TREM2 Mutation Induces Unique Microglial States Associated with Toxic Function in Tauopathy
SSRN Electronic Journal·2019Open Access
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy
Proceedings of the National Academy of Sciences·2018· 242 citedOpen Access
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Frequent Co-authors

Li Gan(37), Yaqiao Li(17), Lay Kodama(13), David Le(13), Lihong Zhan(12), Peter Sohn(10), Faten A. Sayed(10), William W. Seeley(9), Lennart Mucke(9), Tara E. Tracy(8), Maria A. Telpoukhovskaia(8), Binggui Sun(7), Li Fan(7), Sang‐Won Min(6), Sue‐Ann Mok(6), Giovanni Coppola(6), Lea T. Grinberg(6), Sarah Mueller-Steiner(5), Sakura Minami(5), Brian Halabisky(5)