Yasuharu Takagi

National Institutes of Health — United States

Medicine · Health Sciences

25h-index2.4kcitations78works8.02yr avg
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Research Topics

Cardiomyopathy and Myosin Studies(53), Cellular Mechanics and Interactions(32), Muscle Physiology and Disorders(28), Force Microscopy Techniques and Applications(19), Polymer Surface Interaction Studies(6)

Publications78 total

Abstract Fri160: Ca <sup>2+/</sup> Calmodulin Dependent&amp;Independent Regulation of Obscurin Kinase 1
Circulation Research·2025
Filament transport supports contractile steady states of actin networks
2025· 5 citedOpen Access
BPS2025 - Microtubules soften on the sub-millisecond timescale under compressive force
Biophysical Journal·2025
Expression, Purification, and In Vitro Analysis of Myosin
Methods in molecular biology·2024· 1 citedOpen Access
Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track
Proceedings of the National Academy of Sciences·2024· 42 citedOpen Access
Human myosin-7a has multiple distinct regulatory mechanisms that make it an excellent candidate as tension adaptation motor
Biophysical Journal·2024Open Access
Molecular regulatory mechanism of human myosin-7a
Journal of Biological Chemistry·2023· 9 citedOpen Access
Myosin-5 varies its steps along the irregular F-actin track
2023· 3 citedOpen Access
Mechanistic insights into the regulation of human myosin-7a
Biophysical Journal·2023· 1 citedOpen Access
Flagella-like beating of actin bundles driven by self-organized myosin waves
Nature Physics·2022· 20 citedOpen Access
Nanometre resolution stepping pattern and structure of acto-myosin-5a at high ATP reveals new mechanism for processive translocation
Biophysical Journal·2022
General Method to Increase Carboxylic Acid Content on Nanodiamonds
Molecules·2022· 12 citedOpen Access
Myosin-driven Nucleation of Actin Filaments Drives Stereocilia Development Critical for Hearing
2021· 12 citedOpen Access
Human Myosin Vc Is a Low Duty Ratio, Nonprocessive Molecular Motor
UNC Libraries·2021Open Access
Drosophila melanogaster Myosin-18 Represents a Highly Divergent Motor with Actin Tethering Properties
UNC Libraries·2021Open Access
The formin inhibitor SMIFH2 inhibits members of the myosin superfamily
Journal of Cell Science·2021· 96 citedOpen Access
Myosin-Specific Adaptations of In vitro Fluorescence Microscopy-Based Motility Assays
Journal of Visualized Experiments·2021· 1 cited
Myosin-Specific Adaptations of In vitro Fluorescence Microscopy-Based Motility Assays
Journal of Visualized Experiments·2021· 4 cited
A binding protein regulates myosin-7a dimerization and actin bundle assembly
Nature Communications·2021· 33 citedOpen Access
The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness
Journal of Biological Chemistry·2020· 17 citedOpen Access
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Frequent Co-authors

James R. Sellers(33), Neil Billington(18), Adam Fineberg(7), Attila Nagy(7), Keir C. Neuman(7), Jonathan E. Bird(7), Gavin Young(6), Joanna Andrecka(6), Philipp Kukura(6), Rong Liu(6), Yi Yang(6), Thomas B. Friedman(6), Hak‐Sung Jung(5), Andrew Dittmore(5), Peter J. Knight(5), Michelle Peckham(5), Alistair Curd(5), Daniel Cole(4), Earl Homsher(4), Fang Zhang(4)