Seema Bag

Relay Therapeutics (United States) — United States

Computer Science · Physical Sciences

18h-index870citations40works0.02yr avg
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Research Topics

Computational Drug Discovery Methods(7), Synthesis and biological activity(5), Cholinesterase and Neurodegenerative Diseases(5), Nanoplatforms for cancer theranostics(4), Research on Leishmaniasis Studies(4)

Publications40 total

Process Development and Scale-Up of RLY-2139: A Selective CDK2 Inhibitor Targeting ER+/HER2– Breast Cancer
Organic Process Research & Development·2026
From Chiral Separation to Asymmetric Synthesis: Route Scouting and Early Process Development of a Chiral Tetrahydrofuran–Pyrazolamine Intermediate of CDK2 Inhibitor <b>RLY-2139</b>
Organic Process Research & Development·2026
Corrigendum: Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes
Frontiers in Microbiology·2023· 2 citedOpen Access
Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes
Frontiers in Microbiology·2023· 4 citedOpen Access
CCDC 2154912: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Characterization of Triphenylamine and Ferrocenyl Donor‐π‐Donor Vinyl BODIPY Derivatives as Photoacoustic Contrast Agents<sup>†</sup>
Photochemistry and Photobiology·2021· 2 citedOpen Access
Structure–Bioactivity Relationships of Lapatinib Derived Analogs against <i>Schistosoma mansoni</i>
ACS Medicinal Chemistry Letters·2020· 5 citedOpen Access
Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors
ACS Medicinal Chemistry Letters·2020· 26 citedOpen Access
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-<i>b</i>]pyridazines for the Treatment of Human African Trypanosomiasis
Journal of Medicinal Chemistry·2019· 17 citedOpen Access
CCDC 1897292: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
Improvement of Aqueous Solubility of Lapatinib-Derived Analogues: Identification of a Quinolinimine Lead for Human African Trypanosomiasis Drug Development
Journal of Medicinal Chemistry·2018· 37 citedOpen Access
Photophysical and Photoacoustic Properties of Quadrupolar Borondifluoride Curcuminoid Dyes
Chemistry - A European Journal·2017· 33 citedOpen Access
Rational Drug Design, Synthesis and Biological Evaluation of Dihydrofolate Reductase Inhibitors as Antituberculosis Agents
Future Medicinal Chemistry·2015· 16 cited
Sulfonamides as multifunctional agents for Alzheimer’s disease
Bioorganic & Medicinal Chemistry Letters·2014· 87 citedOpen Access
Shining Light on the Dark Side of Imaging: Excited State Absorption Enhancement of a Bis-styryl BODIPY Photoacoustic Contrast Agent
Journal of the American Chemical Society·2014· 95 citedOpen Access
Nonlinear optical properties of multipyrrole dyes
Chemical Physics Letters·2014· 54 citedOpen Access
Exploring the Noninnocent Character of Electron Rich π-Extended 8-Oxyquinolate Ligands in Ruthenium(II) Bipyridyl Complexes
Inorganic Chemistry·2014· 32 cited
BODIPY derivatives as molecular photoacoustic contrast agents
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE·2014· 1 cited
ChemInform Abstract: Catalytic C‐H Bond Activation Reactions
ChemInform·2013
Design, synthesis and biological activity of multifunctional α,β-unsaturated carbonyl scaffolds for Alzheimer’s disease
Bioorganic & Medicinal Chemistry Letters·2013· 54 citedOpen Access
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Frequent Co-authors

Mariam S. Degani(14), Nilesh R. Tawari(11), Béla Török(9), Jonathan Rochford(7), Marianna Török(7), Michael P. Pollastri(7), Lori Ferrins(7), Mathieu Frenette(6), Maryam Hatamimoslehabadi(6), Chandra S. Yelleswarapu(6), Abha Sood(6), Kelly A. Bachovchin(6), Dana M. Klug(6), Melissa J. Buskes(6), Samir Laoui(5), Rekha Tulsan(5), Weihong Zhou(5), Baljinder Singh(5), Stephanie Bellinger‐Buckley(4), Jeffrey La(4)