Edward W. Huber

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.2kcitations75works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(15), Carbohydrate Chemistry and Synthesis(10), Synthesis and Biological Evaluation(10), Fluorine in Organic Chemistry(8), Phenothiazines and Benzothiazines Synthesis and Activities(8)

Publications75 total

“ERS/ESTS CLINICAL GUIDELINES ON FITNESS FOR RADICAL THERAPY IN LUNG CANCER PATIENTS (SURGERY AND CHEMO-RADIOTHERAPY)”. A. BRUNELLI, A. CHARLOUX, C.T. BOLLIGER, G. ROCCO, J-P. SCULIER, G. VARELA, M. LICKER, M.K. FERGUSON, C. FAIVRE-FINN, R.M. HUBER, E.M. CLINI, T. WIN, D. DE RUYSSCHER AND L. GOLDMAN ON BEHALF OF THE EUROPEAN RESPIRATORY SOCIETY AND EUROPEAN SOCIETY OF THORACIC SURGEONS JOINT TASK FORCE ON FITNESS FOR RADICAL THERAPY.<i>EUR RESPIR J</i>2009; 34: 17–41.: Fig. 2—
European Respiratory Journal·2009· 89 citedOpen Access
Chemical Development of MDL 103371:  An <i>N</i>-Methyl-<scp>d</scp>-Aspartate-Type Glycine Receptor Antagonist for the Treatment of Stroke
Organic Process Research & Development·2000· 35 cited
ChemInform Abstract: Constrained Amino Acids. The Synthesis of Glutamine Mimetics.
ChemInform·1997
Constrained amino acids. The synthesis of glutamine mimetics
Tetrahedron Letters·1997· 17 cited
H-19F NOE difference spectroscopy as a tool for structural assignment of positional isomers in fluorine-substituted analogues of FPL 64176
Journal of Fluorine Chemistry·1997· 3 cited
Hydroxyl and Peroxyl Radical Trapping by the Monoamine Oxidase-B Inhibitors deprenyl and MDL 72,974A: Implications for Protection of Biological Substrates
Free Radical Biology and Medicine·1997· 37 cited
ChemInform Abstract: Preparation and Reactions of Optically Active 4‐Hydroxy‐1,3‐dioxolanes: 2‐Hydroxy Aldehyde Equivalents.
ChemInform·1996
ChemInform Abstract: Constrained Amino Acids, an Approach to the Synthesis of 3‐Substituted Prolines.
ChemInform·1996
Design of a Fluoro-olefin Cytidine Nucleoside as a Bioprecursor of a Mechanism-Based Inhibitor of Ribonucleotide Reductase
ACS symposium series·1996· 7 cited
Constrained amino acids. An approach to the synthesis of 3-substituted prolines
Tetrahedron Letters·1996· 43 cited
Unusual Maxima in HPLC Retention of an Homologous Series Consisting of Longer Alkyl Chain Substitutions
Analytical Chemistry·1996
Stereospecific synthesis of 1-fluoro olefins via (fluorovinyl)stannanes and an unequivocal NMR method for the assignment of fluoro olefin geometry
Tetrahedron·1996· 119 cited
ChemInform Abstract: Synthesis of FPL 64176 by 1,3‐Dipolar Cycloaddition.
ChemInform·1995
ChemInform Abstract: Reaction of Ninhydrin with β‐Dicarbonyl Compounds.
ChemInform·1995
ChemInform Abstract: Reinvestigation of Synthetic Routes to 1,3,4‐Benzoxadiazepin‐5‐ones and 1,3‐Benzoxazepines.
ChemInform·1995
Synthesis of FPL 64176 by 1,3-Dipolar Cycloaddition
The Journal of Organic Chemistry·1995· 19 cited
Long‐range fluorine‐proton coupling in 1,2,4‐triazole derivatives
Journal of Heterocyclic Chemistry·1995· 8 cited
Reaction of ninhydrin with β‐dicarbonyl compounds
Journal of Heterocyclic Chemistry·1995· 36 cited
Inhibition of Human Neutrophil Elastase. 3. An Orally Active Enol Acetate Prodrug
Journal of Medicinal Chemistry·1995· 19 citedOpen Access
Inhibition of Human Neutrophil Elastase with Peptidyl Electrophilic Ketones. 2. Orally Active PG-Val-Pro-Val Pentafluoroethyl Ketones
Journal of Medicinal Chemistry·1994· 49 citedOpen Access
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Frequent Co-authors

Norton P. Peet(10), John M. Kane(8), William R. Heineman(7), Gary A. Flynn(7), Philippe Bey(6), James R. McCarthy(4), Michael R. Angelastro(4), Robert A. Farr(4), Timothy P. Burkholder(4), Robert J. Barbuch(4), Christopher R. Dalton(4), Donald P. Matthews(3), Joseph P. Burkhart(3), Jeffrey S. Sabol(3), Richard A. Schnettler(3), Dirk Friedrich(3), Shyam Sunder(3), Prasad S. Sunkara(2), F. M. LASKOVICS(2), Larry E. Baugh(2)