C. J. L. Lock

McMaster University — Canada

Medicine · Health Sciences

40h-index4.7kcitations254works0.02yr avg
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Research Topics

Metal complexes synthesis and properties(83), Crystal structures of chemical compounds(46), Magnetism in coordination complexes(36), Organometallic Complex Synthesis and Catalysis(35), Radiopharmaceutical Chemistry and Applications(28)

Publications254 total

Model of the most abundant DNA interstrand cross-link of Transplatin: X-ray structures of two modifications and H bonding behavior in the solid state and in solution of trans-[Pt(NH3)2(1-MeC-N3)(9-EtGH-N7)](ClO4)2·nH2O (1-MeC=1-methylcytosine; 9-EtGH=9-ethylguanine)
Inorganica Chimica Acta·2002· 26 cited
The synthesis, NMR and X-ray analysis of tris(1-ethyl-2-isopropylimidazol-5-yl)phosphine gold (I)-2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside, a bifunctional auranofin analogue
Inorganica Chimica Acta·1998· 13 cited
Structure and dynamics of azapropazone derivatives studied by crystallography and nuclear magnetic resonance
Canadian Journal of Chemistry·1998· 1 cited
CCDC 129438: Experimental Crystal Structure Determination
The Cambridge Structural Database·1998Open Access
Monoammonium Bis(<scp>D</scp>-penicillaminato-<i>S</i>)aurate(I) 3.667-Hydrate
Acta Crystallographica Section C Crystal Structure Communications·1997· 13 cited
<i>cyclo</i>-Hexakis[(2,4,6-triisopropylthiophenolato-<i>S</i>:<i>S</i>)gold(I)] Diethyl Ether Solvate
Acta Crystallographica Section C Crystal Structure Communications·1997· 24 cited
Bis(triphenylphosphine sulfide-<i>S</i>)gold(I) Difluorophosphate(V)
Acta Crystallographica Section C Crystal Structure Communications·1997· 8 cited
Cyclic Metal Complexes of Nucleobases and Other Heterocycles: Molecular Boxes, Rectangles, and Hexagons
Angewandte Chemie International Edition in English·1997· 91 cited
Cyclische Metallkomplexe mit Nucleobasen und anderen Heterocyclen: molekulare Schachteln, Rechtecke und Sechsecke
Angewandte Chemie·1997· 21 cited
Do You Really Know What Your Drug Looks Like or How it Reacts?
1997· 1 cited
ChemInform Abstract: Do You Really Know What Your Drug Looks Like or How It Reacts?
ChemInform·1996
In memoriam
Inflammopharmacology·1996
The synthesis and high-resolution NMR spectroscopy of ethyl <i>N</i>-(2-triphenylmethylthio)ethanoyl-<i>O</i>-{4′-[4″-(1″-bis(2″′-chloroethyl)amino)phenyl]butanoyl}-<scp>L</scp>-seryl-<i>S</i>-benzyl-<scp>L</scp>-cysteine: a chelate–chlorambucil complex for use as a ligand for <sup>99m</sup>Tc radio-imaging
Canadian Journal of Chemistry·1996· 10 cited
<i>N</i>10-(2′-Mercaptoethanoyl)-2,2,5,5-tetramethyl-3,4-diathia-7,10-diaza-bicyclo[5.3.0]decane and its reaction with oxotrichlorobis(triphenylphosphine)rhenium(V)
Canadian Journal of Chemistry·1996· 8 cited
Do you really know what your drug looks like or how it reacts?
Inflammopharmacology·1996· 1 cited
Concerning the nature of the gold-containing anti-arthritic drug, myochrysine
Chemical Communications·1996· 12 cited
Synthesis and Structure of Oxo(2-(1'-methyl-1'-mercaptoethyl)-3-(5''-methyl-5''-mercapto- 3''-(dehydroaza)hexyl)thiazolidinato-N3,N3'',S1',S5'')technetium(V) , TcO(C12H23N2S3): Unusual Formation of a Thiazolidine Ring
Inorganic Chemistry·1995· 9 cited
Unusual hydrogen bonding patterns of N<sup>7</sup>metallated, N<sup>1</sup>deprotonated guanine nucleobases: acidity constants of cis-[Pt(NH<sub>3</sub>)<sub>2</sub>(Hegua)<sub>2</sub>]<sup>2+</sup>and crystal structures of cis-[Pt(NH<sub>3</sub>)<sub>2</sub>(egua)<sub>2</sub>]·4H<sub>2</sub>O and cis-[Pt(NH<sub>3</sub>)<sub>2</sub>(egua)<sub>2</sub>]· Hegua·7H<sub>2</sub>O (Hegua = 9-ethylguanine)
Journal of the Chemical Society Dalton Transactions·1995· 54 cited
ChemInform Abstract: Studies of Nonsteroidal Anti‐Inflammatory Drugs: Azapropazone.
ChemInform·1994
The interaction of <scp>D</scp>-penicillamine with aldehydes and ketones: 2-phenyl-5,5-dimethylthiazolidine-4-carboxylic acid
Canadian Journal of Chemistry·1994· 4 cited
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Frequent Co-authors

Bernhard Lippert(19), R. Faggiani(18), Barnett Rosenberg(8), H. E. Howard-Lock(7), Graham Turner(6), R.A. Speranzini(5), Pierre Pilon(4), Kenneth J. Franklin(4), Maruta Zvagulis(3), Alan Davison(3), Alun G. Jones(3), Graham Turner(3), R. J. Gillespie(3), Nigel P. Johnson(2), G. Wilkinson(2), Walter F. Kean(2), Gabriele Raudaschl(2), Gary J. Schrobilgen(2), Michael J. Abrams(2), James F. Britten(2)