Gavril W. Pasternak

Memorial Sloan Kettering Cancer Center — United States

Neuroscience · Life Sciences

32h-index4.3kcitations54works0.02yr avg
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Research Topics

Neuropeptides and Animal Physiology(37), Receptor Mechanisms and Signaling(35), Pharmacological Receptor Mechanisms and Effects(21), Pain Mechanisms and Treatments(17), Neuroscience and Neuropharmacology Research(6)

Publications54 total

277 REORGANIZATION OF DRG NEURONS FOLLOWING CHRONIC SCIATIC NERVE CONSTRICTION INJURY: CORRELATION WITH TOPICAL MORPHINE AND LIDOCAINE ANALGESIA
European Journal of Pain·2007
The Molecular and Behavioral Pharmacology of the Orphanin FQ/Nociceptin Peptide and Receptor Family
Pharmacological Reviews·2001· 436 citedOpen Access
Molecular cloning and pharmacological characterization of the rat sigma1 receptor11Abbreviations: DTG, N,N′-di(o-tolyl-guanidine); HA, hemagglutinin; RT-PCR, reverse transcriptase-polymerase chain reaction; RACE, rapid amplification of cDNA ends; and CHO, Chinese hamster ovary.
Biochemical Pharmacology·2001· 120 cited
Carboxyl terminal peptides derived from prepro-orphanin FQ/nociceptin (ppOFQ/N) are produced in the hypothalamus and possess analgesic bioactivities
Brain Research·2001· 16 cited
Incomplete cross tolerance and multiple mu opioid peptide receptors
Trends in Pharmacological Sciences·2001· 212 cited
Antagonism of heroin and morphine self-administration in rats by the morphine-6β-glucuronide antagonist 3-O-methylnaltrexone
European Journal of Pharmacology·1999· 30 cited
Pharmacological characterization of morphine-6-sulfate and codeine-6-sulfate
Brain Research·1999· 36 cited
Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms
Brain Research·1999· 17 cited
Peripheral orphanin FQ/Nociceptin analgesia in the mouse
Life Sciences·1999· 53 cited
Morphine-6β-Glucuronide-Induced Hyperphagia: Characterization of Opioid Action By Selective Antagonists and Antisense Mapping in Rats
Journal of Pharmacology and Experimental Therapeutics·1998· 14 cited
Antinociceptive analogs of orphanin FQ/nociceptin(1–11)
Life Sciences·1998· 19 cited
Antisense mapping of opioid receptor clones: effects upon 2-deoxy-d-glucose-induced hyperphagia
Brain Research·1998· 16 cited
Orphanin FQ/nociceptin analgesia in the rat
Brain Research·1998· 50 citedOpen Access
Antisense Mapping of MOR-1 in Rats: Distinguishing between Morphine and Morphine-6β-glucuronide Antinociception
Journal of Pharmacology and Experimental Therapeutics·1997· 44 cited
Antisense mapping DOR-1 in mice: further support for δ receptor subtypes
Brain Research·1997· 39 cited
Spinal analgesic activity of orphanin FQ/nociceptin and its fragments
Neuroscience Letters·1997· 132 cited
Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance.
Journal of Pharmacology and Experimental Therapeutics·1996· 96 cited
Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits.
Molecular Pharmacology·1996· 117 cited
Perspectives on the N-Methyl-?-Aspartate/Nitric Oxide Cascade and Opioid Tolerance
Neuropsychopharmacology·1995· 87 cited
Mapping of opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology
Trends in Pharmacological Sciences·1995· 172 cited
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Frequent Co-authors

Grace C. Rossi(11), Kelly M. Standifer(6), Liza Leventhal(5), Dennis Paúl(4), J A Clark(3), K. Spiegel(3), Richard J. Bodnar(3), Yuri Kolesnikov(3), Charles E. Inturrisi(2), Geoffrey Ling(2), Stephen H. Lockhart(2), R A Houghten(2), Michael A. King(2), Elliot F. Hahn(2), Benjamin A. Adler(2), Wendy Su(2), Nicole L. Johnson(2), Amy Zuckerman(2), John P. Mathis(2), Jeffrey S. Mogil(1)