Karen Hobson

QIMR Berghofer Medical Research Institute — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index2.1kcitations17works0.02yr avg
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Research Topics

DNA Repair Mechanisms(13), Carcinogens and Genotoxicity Assessment(7), Cancer-related Molecular Pathways(5), RNA and protein synthesis mechanisms(2), BRCA gene mutations in cancer(2)

Publications17 total

Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell-line phenotypic variability
Breast Cancer Research and Treatment·2006· 8 cited
Characterization of the breast cancer associated <i>ATM</i> 7271T&gt;G (V2424G) mutation by gene expression profiling
Genes Chromosomes and Cancer·2006· 20 cited
BRCA1-BARD1 Complexes Are Required for p53Ser-15 Phosphorylation and a G1/S Arrest following Ionizing Radiation-induced DNA Damage
Journal of Biological Chemistry·2004· 165 citedOpen Access
Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent Phosphorylation of Chk1 on Ser-317 in Response to Ionizing Radiation
Journal of Biological Chemistry·2003· 301 citedOpen Access
Ataxia Telangiectasia Mutated (ATM) Kinase and ATM and Rad3 Related Kinase Mediate Phosphorylation of Brca1 at Distinct and Overlapping Sites
Journal of Biological Chemistry·2001· 188 citedOpen Access
Transactivation-deficient p73α (p73Δexon2) inhibits apoptosis and competes with p53
Oncogene·2001· 120 cited
Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells
Oncogene·1999· 45 cited
ATM associates with and phosphorylates p53: mapping the region of interaction
Nature Genetics·1998· 497 cited
Cloning and Expression of the Ataxia–Telangiectasia Gene in Baculovirus
Biochemical and Biophysical Research Communications·1998· 17 cited
Interaction between ATM protein and c-Abl in response to DNA damage
Nature·1997· 479 cited
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms
Oncogene·1997· 186 cited
Defective Signaling through the B Cell Antigen Receptor in Epstein-Barr Virus-transformed Ataxia-Telangiectasia Cells
Journal of Biological Chemistry·1997· 42 citedOpen Access
Watters, D. et al. Cellular localization of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms. Oncogene 14, 1911-1921
1997· 7 cited
Rapamycin resistance in ataxia-telangiectasia.
PubMed·1996· 15 cited
Cloning and characterization of cDNA encoding a human arginyl-tRNA synthetase
Gene·1995· 16 cited
Comparative study of radiation-induced G2 phase delay and chromatid damage in families with ataxia-telangiectasia
Cancer Genetics and Cytogenetics·1994· 15 cited
Use of DNA-protein interaction to isolate specific genomic DNA sequences
Analytical Biochemistry·1991· 7 cited

Frequent Co-authors

Martin F. Lavin(12), Kum Kum Khanna(10), Magtouf Gatei(8), Dianne Watters(6), Kevin J. Spring(5), Sergei Kozlov(4), Shaun P. Scott(4), Heather Beamish(4), Philip Chen(4), Kum Kum Khanna(3), Padmini S. Kedar(3), Áine Farrell(3), Kienan I. Savage(2), Geoffrey W. Birrell(2), Deborah Stenzel(2), Ning Zhang(2), Jonathan Ramsay(2), Richard A. Gatti(2), Anna Marsh(2), Georgia Chenevix‐Trench(2)