J. Middleton

Medicine · Health Sciences

12h-index1.5kcitations27works0.02yr avg
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Research Topics

Osteoarthritis Treatment and Mechanisms(8), Cell Adhesion Molecules Research(7), Chemokine receptors and signaling(4), Growth Hormone and Insulin-like Growth Factors(3), Bone health and treatments(3)

Publications27 total

Mechanism of Chemokine-Induced Leukocyte Adhesion and Emigration
2020· 1 cited
Handy DNA Nucleotide Model
The American Biology Teacher·2019Open Access
Cell Receptor-Ligand Interaction, Signalling, Activation and Apoptosis [25-29]: 25. Expression of GPR15/BOB on Monocytes and Neutrophils in Peripheral Blood and on Monocyte/Macrophages in Synovial Tissue and Synovial Fluid of Rheumatoid Arthritis Patients
Lara D. Veeken·2010Open Access
The anti-inflammatory protein TSG-6 displaces the chemokine CXCL8 from neutrophils in the rheumatoid synovium.
Research Explorer (The University of Manchester)·2005
Endothelial Cell “Memory” of Inflammatory Stimulation: Human Venular Endothelial Cells Store Interleukin 8 in Weibel-Palade Bodies
The Journal of Experimental Medicine·1998· 220 citedOpen Access
Endothelial presentation of IL‐8 to neutrophils: evidence for chemokine transcytosis
International Journal of Experimental Pathology·1998· 2 citedOpen Access
Transcytosis and Surface Presentation of IL-8 by Venular Endothelial Cells
Cell·1997· 732 citedOpen Access
Insulin-like growth factor (IGF) receptor, IGF-I, interleukin-1 beta (IL-1 beta), and IL-6 mRNA expression in osteoarthritic and normal human cartilage.
Journal of Histochemistry & Cytochemistry·1996· 82 citedOpen Access
Some aspects of IL-8 pathophysiology III: chemokine interaction with endothelial cells
Journal of Leukocyte Biology·1996· 127 cited
The Expression of mRNA for Insulin-Like Growth Factors and Their Receptor in Giant Cell Tumors of Human Bone
Clinical Orthopaedics and Related Research·1996· 12 cited
Osteoblasts and osteoclasts in adult human osteophyte tissue express the mRNAs for insulin-like growth factors I and II and the type 1 IGF receptor
Bone·1995· 105 cited
Upregulation of insulin-like growth factor I gene expression in the lesions of osteoarthritic human articular cartilage.
Annals of the Rheumatic Diseases·1992· 91 citedOpen Access
Prostaglandin F2a rapidly stimulates tyrosine phosphorylation in MC3T3-EL osteoblasts: Role in mitogenesis
Bone and Mineral·1992
Low temperature SEM and X-ray microanalysis of mammalian hyaline cartilage
Bone·1992
An inexpensive detector for water‐vapour in the low temperature scanning electron microscope
Journal of Electron Microscopy Technique·1989· 3 cited
Cation movement in rat articular and non-articular cartilage and in isolated chondrocytes: Calcium influx and efflux
Comparative Biochemistry and Physiology Part A Physiology·1988
Low temperature and conventional scanning electron microscopic observations of dog femoral condylar cartilage surface after anterior cruciate ligament division.
Annals of the Rheumatic Diseases·1985· 17 citedOpen Access
Low Temperature and Conventional Scanning Electron Microscopy of Human Urothelium
British Journal of Urology·1985· 10 cited
Demonstration by X-Ray Microprobe Analysis of Relationship Between Chondrocytes and Tertiary Surface Structure of Hyaline Articular Cartilage
Connective Tissue Research·1984· 9 cited
Euploidization of human hepatocytes from donors of different ages and both sexes compared with those from cases of werner's syndrome and progeria
Experimental Gerontology·1984· 14 cited
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Frequent Co-authors

K. Oates(7), Antal Rot(5), P. B. Gahan(5), D. L. Gardner(4), C R Orford(4), Jonathan Wintle(3), Elin Hub(3), Patricia OʼConnor(3), Stuart J. D. Neil(2), Barbara Wolff(2), Nighat Arnott(2), Susan Walsh(2), J.N. Beresford(2), Jenny A. Tyler(2), D L Gardner(2), S. Hunt(2), Angela Midgley(2), MW Beresford(2), Ian Clark‐Lewis(1), Henrietta D. Moore(1)