Seung Shin Yu

Helixmith (South Korea) — South Korea

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index571citations26works0.02yr avg
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Research Topics

Virus-based gene therapy research(13), RNA Interference and Gene Delivery(10), CRISPR and Genetic Engineering(6), Viral Infectious Diseases and Gene Expression in Insects(6), HIV Research and Treatment(3)

Publications26 total

Intramuscular delivery of HGF-expressing recombinant AAV improves muscle integrity and alleviates neurological symptoms in the nerve crush and SOD1-G93A transgenic mouse models
Biochemical and Biophysical Research Communications·2019· 14 citedOpen Access
Intrathecal delivery of recombinant AAV1 encoding hepatocyte growth factor improves motor functions and protects neuromuscular system in the nerve crush and SOD1-G93A transgenic mouse models
Acta Neuropathologica Communications·2019· 19 citedOpen Access
Generation of Antigen-Specific Cytotoxic T Lymphocytes with Peripheral B Cells Activated By α-Galactosylceramide
Blood·2014
Improvement of pharmacokinetic, pharmacodynamic and thrombopoietic activities of human interleukin-11 mutein by PEGylation.
Journal of Clinical Oncology·2012
Multicenter, randomized study of genetically modified recombinant human interleukin-11 to prevent chemotherapy-induced thrombocytopenia in cancer patients receiving chemotherapy
Supportive Care in Cancer·2011· 41 cited
Retroviral Gene Therapy for X-linked Chronic Granulomatous Disease: Results From Phase I/II Trial
Molecular Therapy·2011· 102 citedOpen Access
Development of an <i>in vitro</i> cell culture assay system for measuring the activation of a neighbouring gene by the retroviral vector
The Journal of Gene Medicine·2008· 1 cited
Transient gene expression mediated by integrase-defective retroviral vectors
Biochemical and Biophysical Research Communications·2008· 19 cited
Control of Splicing Efficiency by the Mouse Histone H2a Element in a Murine Leukemia Virus–based Retroviral Vector
Molecular Therapy·2006· 18 citedOpen Access
Intrasplenic electro-transfer of IL-4 encoding plasmid DNA efficiently inhibits rat experimental allergic encephalomyelitis
Biochemical and Biophysical Research Communications·2006· 10 cited
Factors affecting the performance of different long terminal repeats in the retroviral vector
Biochemical and Biophysical Research Communications·2006· 10 cited
824. Control of Splicing Efficiency by the Mouse Histone H2a Element in an MLV-Based Retroviral Vector
Molecular Therapy·2006
817. Rapid and Efficient Titration of Retroviral Vectors Using Quantitative Real-Time PCR
Molecular Therapy·2006Open Access
Electrotransfer of human IL‐1Ra into skeletal muscles reduces the incidence of murine collagen‐induced arthritis
The Journal of Gene Medicine·2004· 29 cited
Effects of IL-1β on gene expression in human rheumatoid synovial fibroblasts
Biochemical and Biophysical Research Communications·2004· 57 cited
Protection against collagen-induced arthritis by electrotransfer of an expression plasmid for the interleukin-4
Biochemical and Biophysical Research Communications·2004· 36 cited
Factors affecting retrovirus‐mediated gene transfer to human CD34+ cells
The Journal of Gene Medicine·2004· 12 cited
Development of enzyme-linked immunosorbent assay for detecting antibodies to replication-competent murine leukemia virus
Journal of Virological Methods·2004· 3 cited
Construction of a retroviral vector production system with the minimum possibility of a homologous recombination
Gene Therapy·2003· 27 cited
Construction of a high efficiency retroviral vector for gene therapy of Hunter's syndrome
The Journal of Gene Medicine·2002· 18 cited
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Frequent Co-authors

Sunyoung Kim(21), Sujeong Kim(16), Youngtae Hong(7), Seong‐Hyun Ho(5), Karim Lee(5), Jae‐Gyun Jeong(4), Woong Hahn(3), Eun Jin Park(3), Hwang-Jae Lee(3), Dong‐Sik Kim(3), Jong‐Mook Kim(3), Jun-Tae Lee(3), Hyoung Jin Kang(2), Seon Hee Kim(2), Duk‐Kyung Kim(2), Kazuyuki Dan(2), Junichi Mineno(2), Sang Hwan Lee(2), Subin Kim(2), Nayeon Lee(2)