J. BRLIK

Chemistry · Physical Sciences

12h-index411citations45works0.02yr avg
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Research Topics

Chemical synthesis and alkaloids(19), Alkaloids: synthesis and pharmacology(18), Advanced Synthetic Organic Chemistry(12), Analytical Chemistry and Chromatography(6), Organophosphorus compounds synthesis(5)

Publications45 total

[From routine acylation towards stable sigma-complexes of pyrimidine: carbon protonation of the pyrimdine-ring].
PubMed·2004
Protonation of the Pyrimidine Ring at the C(5) Position:  Formation of a Stable Cationic σ-Complex
Journal of the American Chemical Society·2003· 17 cited
[Light- and temperature-induced degradation of fumagillin].
PubMed·2003· 4 cited
ChemInform Abstract: Synthesis of Vinca Alkaloids and Related Compounds. Part 95. Attempted Build‐Up of the Aspidospermidine Skeleton by [4 + 2] Cycloaddition. Some Unexpected Reactions, and Formation of a New Ring System.
ChemInform·2001
Synthesis of Vinca Alkaloids and Related Compounds 95. Attempted Build-up of the Aspidospermidine Skelton by [4+2] Cycloaddition. Some Unexpected Reactions, and Formation of a New Ring System
Heterocycles·2001· 9 citedOpen Access
ChemInform Abstract: Synthesis of Vinca Alkaloids and Related Compounds. Part 94. Epimerization of Compounds with Aspidospermane and D‐Secoaspidospermane Skeleton.
ChemInform·2000
Synthesis of vinca alkaloids and related compounds part 94. Epimerization of compounds with aspidospermane and <i>D</i>‐secoaspidospermane skeleton
Journal of Heterocyclic Chemistry·2000· 12 cited
2.3. Mass spectrometry in impurity profiling
Progress in pharmaceutical and biomedical analysis·2000· 4 cited
Estimation of impurity profiles of drugs and related materials
Journal of Pharmaceutical and Biomedical Analysis·1998· 29 cited
Estimation of impurity profiles of drugs and related materials Part 18. Impurities and degradation products of mazipredone
Journal of Pharmaceutical and Biomedical Analysis·1998· 24 cited
ChemInform Abstract: Synthesis of Vinca Alkaloids and Related Compounds. Part 90. New Results in the Synthesis of Alkaloids with the Aspidospermane Skeleton. First Total Synthesis of (.+‐.)‐3‐Oxominovincine.
ChemInform·1998
ChemInform Abstract: Synthesis of Vinca Alkaloids and Related Compounds. Part 89. Some Unexpected Reactions of Compounds Containing the D‐seco‐Aspidospermane Ring System.
ChemInform·1998
Synthesis of Vinca Alkaloids and Related Compounds, Part LXXXIX. Some UnexpectedReactions of Compounds Containing the D-Seco-aspidospermane Ring System
Heterocycles·1998· 4 citedOpen Access
Synthesis of Vinca Alkaloids and Related Compounds. 90.<sup>1</sup> New Results in the Synthesis of Alkaloids with the Aspidospermane Skeleton. First Total Synthesis of (±)-3-Oxominovincine
The Journal of Organic Chemistry·1997· 36 cited
Drug impurity profiling strategies.
PubMed·1997· 72 cited
Estimation of impurity profiles of drugs and related materials Part 16: Identification of the side-products of the ethinylation step in the synthesis of contraceptive gestogens
Journal of Pharmaceutical and Biomedical Analysis·1997· 22 cited
Estimation of impurity profiles of drugs and related materials Part 15. Identification of minor impurities in cimetidine
Journal of Pharmaceutical and Biomedical Analysis·1996· 20 cited
ChemInform Abstract: Synthesis of Vinca Alkaloids and Related Compounds. Part 74. Reaction of (.+‐.)‐1α‐Ethyl‐1β‐(mesyloxymethyl)‐1,2,3,4,6,7,12,12b. beta.‐octahydroindolo(2,3‐a)quinolizine with Hydride and N Nucleophiles.
ChemInform·1996
ChemInform Abstract: Synthesis of Vinca Alkaloids and Related Compounds. Part 75. Reaction of (.+‐.)‐1α‐Ethyl‐1β‐(mesyloxymethyl)‐1,2,3,4,6,7,12,12b. beta.‐octahydroindolo(2,3‐a)quinolizine with Ambident and S Nucleophiles.
ChemInform·1996
Synthesis of Vinca Alkaloids and Related Compounds, 76.<sup>1</sup>Synthesis and Ring Transformations of Compounds with the Aspidospermane- and D-Noraspidospermane Skeleton. A Formal Synthesis Of (±)-12-Demethoxy-N(1)-Acetyl-Cylindrocarine
Natural product letters·1995· 19 cited
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Frequent Co-authors

M. KAJTAR‐PEREDY(22), Lajos Szabó(20), István Greiner(16), Csaba Szántay(14), G. KALAUS(11), György Kalaus(9), Imre Juhász(8), Sándor Gǒrög(5), György Keglevich(5), F. JANKE(5), Cs. Szántay(5), A. Csehi(4), Péter Horváth(4), Katalin Varga(4), N. MALKIEH(4), L. TOEKE(4), Mónika Babják(3), Gábor Balogh(3), Ferenc Dravecz(3), Anna Laukó(3)