Roger H. Unger

VA North Texas Health Care System — United States

Medicine · Health Sciences

115h-index45.2kcitations483works0.02yr avg
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Research Topics

Pancreatic function and diabetes(224), Diabetes Treatment and Management(139), Diabetes Management and Research(93), Metabolism, Diabetes, and Cancer(83), Diabetes and associated disorders(75)

Publications483 total

Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets
Proceedings of the National Academy of Sciences·2021· 45 citedOpen Access
Obesity dysregulates fasting-induced changes in glucagon secretion
Journal of Endocrinology·2019· 80 citedOpen Access
Fasting-Induced Changes in Glucagon Secretion Are Dysregulated in Obesity
Diabetes·2018· 2 cited
Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice
Cell Reports·2018· 66 citedOpen Access
Effect of a glucagon receptor antibody (REMD‐477) in type 1 diabetes: A randomized controlled trial
Diabetes Obesity and Metabolism·2017· 63 citedOpen Access
Dapagliflozin suppresses glucagon signaling in rodent models of diabetes
Proceedings of the National Academy of Sciences·2017· 32 citedOpen Access
Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice
Cell Metabolism·2017· 186 citedOpen Access
Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade
Diabetes·2017· 31 citedOpen Access
Glucagon antagonism in islet cell proliferation
Proceedings of the National Academy of Sciences·2017· 9 citedOpen Access
Insulin and Glucagon: Partners for Life
Endocrinology·2017· 88 citedOpen Access
Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists
Diabetes Care·2016· 87 citedOpen Access
Glucagon is the key factor in the development of diabetes
Diabetologia·2016· 165 citedOpen Access
MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk
Diabetes·2016· 67 citedOpen Access
Glucagon therapeutics: Dawn of a new era for diabetes care
Diabetes/Metabolism Research and Reviews·2016· 26 cited
Regulation of fatty acid homeost
2016
An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production
SLAS DISCOVERY·2015· 8 citedOpen Access
A New Biology of Diabetes Revealed by Leptin
Cell Metabolism·2015Open Access
Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway
Proceedings of the National Academy of Sciences·2015· 112 citedOpen Access
A New Biology of Diabetes Revealed by Leptin
Cell Metabolism·2014· 34 citedOpen Access
Alveolar–capillary adaptation to chronic hypoxia in the fatty lung
Acta Physiologica·2014· 12 citedOpen Access
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Frequent Co-authors

Lelio Orci(11), Yan-Ting Zhou(8), May-Yun Wang(7), Michio Shimabukuro(6), Anna M. Eisentraut(6), Christopher B. Newgard(6), Moritake Higa(4), Makoto Ohneda(3), Kazunori Koyama(3), Ronald G. Victor(3), Lidia S. Szczepaniak(3), Philipp E. Scherer(3), Young Lee(3), Leonard L. Madison(3), Young Lee(3), Paul Grayburn(2), E Aguilar-Parada(2), Walter A. Müller(2), Ying Lee(2), John H. Johnson(2)