Hiromi Nagasaki

Tokyo Medical and Dental University — Japan

Medicine · Health Sciences

12h-index634citations16works0.02yr avg
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Research Topics

Genetic factors in colorectal cancer(9), Colorectal Cancer Treatments and Studies(3), Digestive system and related health(3), DNA Repair Mechanisms(2), Epigenetics and DNA Methylation(2)

Publications16 total

Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models
British Journal of Cancer·2018· 14 citedOpen Access
Plasma microRNA-103, microRNA-107, and microRNA-194 levels are not biomarkers for human diffuse gastric cancer
Journal of Cancer Research and Clinical Oncology·2016· 13 citedOpen Access
<i>Insulin‐like growth factor 2</i> hypomethylation of blood leukocyte DNA is associated with gastric cancer risk
International Journal of Cancer·2012· 62 cited
DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients
International Journal of Cancer·2008· 106 citedOpen Access
Methylation of the Calcium Channel-Related Gene, CACNA2D3, Is Frequent and a Poor Prognostic Factor in Gastric Cancer
Gastroenterology·2008· 87 citedOpen Access
Absorption, Tissue Distribution, Excretion, and Metabolism of Clothianidin in Rats
Journal of Agricultural and Food Chemistry·2003· 48 cited
β-Catenin and adenomatous polyposis coli (APC) mutations in adenomas from hereditary non-polyposis colorectal cancer patients
Cancer Letters·2000· 27 cited
Distinct Expression ofCDX2 andGATA4/5, Development-Related Genes, in Human Gastric Cancer Cell Lines
Molecular Carcinogenesis·2000· 51 citedOpen Access
Frequent Allelic Imbalance on Chromosome 18q21 in Early Superficial Colorectal Cancers
Japanese Journal of Cancer Research·1999· 8 citedOpen Access
Predominant germ-line mutation of thehMSH2 gene in Japanese hereditary non-polyposis colorectal cancer kindreds
International Journal of Cancer·1999· 27 cited
A Core Promoter and a Frequent Single-Nucleotide Polymorphism of the Mismatch Repair GenehMLH1
Biochemical and Biophysical Research Communications·1999· 95 cited
Genetic alterations are frequent in APC but rare in the TGF-β type II receptor gene in cancer in adenomas of the colon
Cancer Letters·1998· 10 cited
222 Genetic analyses of skin tumours developed in a patient with hereditary nonpolyposis colorectal cancer (HNPCC)
Journal of Dermatological Science·1997
Structure of the human genomic TGF-β type II receptor locus and its two-hit mutations in hereditary nonpolyposis colorectal cancer
日本分子生物学会年会プログラム・講演要旨集·1996
Frequent Microsatellite Instabilities and Analyses of the Related Genes in Familial Gastric Cancers
Japanese Journal of Cancer Research·1996· 46 citedOpen Access
Loss or Somatic Mutations of <i>hMSH2</i> Occur in Hereditary Nonpolyposis Colorectal Cancers with <i>hMSH2</i> Germline Mutations
Japanese Journal of Cancer Research·1996· 40 citedOpen Access

Frequent Co-authors

Yasuhito Yuasa(13), Yoshimitsu Akiyama(13), Tadashi Nomizu(5), Takeo Iwama∥(4), Shu Shimada(3), Osmar Kenji Yagi(3), Takehisa Iwai(3), Kazuyuki Kojima(2), Tatsuyuki Kawano(2), Kazuo Maruyama(2), Isao Oze(2), Miki Watanabe(2), Keitaro Matsuo(2), Y Yuasa(2), Shi‐Long Lu(2), Shozo Baba(2), Takehiro Arai(2), Yutaka Hashimoto(1), Touichirou Takizawa(1), Kenichi Sugihara(1)