Guichun Xing

Beijing Proteome Research Center — China

Medicine · Health Sciences

37h-index3.7kcitations73works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(18), Ubiquitin and proteasome pathways(18), Cancer-related gene regulation(10), TGF-β signaling in diseases(9), Endoplasmic Reticulum Stress and Disease(7)

Publications73 total

Erratum: CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation
Oncogene·2016· 40 citedOpen Access
Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis
Nature Cell Biology·2015· 223 cited
ARF-mediated SUMOylation of Apak antagonizes ubiquitylation and promotes its nucleolar accumulation to inhibit 47S pre-rRNA synthesis
Journal of Molecular Cell Biology·2015· 5 citedOpen Access
NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling
Cellular Signalling·2014· 28 cited
p53 Degradation by a Coronavirus Papain-like Protease Suppresses Type I Interferon Signaling
Journal of Biological Chemistry·2014· 116 citedOpen Access
CKIP-1 suppresses the adipogenesis of mesenchymal stem cells by enhancing HDAC1-associated repression of C/EBPα
Journal of Molecular Cell Biology·2014· 38 citedOpen Access
Selective Small Molecule Compounds Increase BMP-2 Responsiveness by Inhibiting Smurf1-mediated Smad1/5 Degradation
Scientific Reports·2014· 80 citedOpen Access
The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis
Nature Communications·2014· 204 citedOpen Access
CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation
Cell Research·2014· 74 citedOpen Access
The HECT Type Ubiquitin Ligase NEDL2 Is Degraded by Anaphase-promoting Complex/Cyclosome (APC/C)-Cdh1, and Its Tight Regulation Maintains the Metaphase to Anaphase Transition
Journal of Biological Chemistry·2013· 46 citedOpen Access
CKIP-1 acts as a colonic tumor suppressor by repressing oncogenic Smurf1 synthesis and promoting Smurf1 autodegradation
Oncogene·2013· 38 citedOpen Access
Integrated analysis of genomics and proteomics reveals that CKIP-1 is a novel macrophage migration regulator
Biochemical and Biophysical Research Communications·2013· 15 cited
Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins
Biochemical and Biophysical Research Communications·2013· 13 cited
CKIP‐1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation
EMBO Reports·2012· 17 citedOpen Access
N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents
Cell Research·2012· 25 citedOpen Access
Murine calvaria-derived progenitor cells express high levels of osterix and lose their adipogenic capacity
Biochemical and Biophysical Research Communications·2012· 2 cited
Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis
EMBO Reports·2012· 22 citedOpen Access
DNA damage stress induces the dissociation of Smurf1/2 from MDM2 in a slow manner
Chinese Science Bulletin·2011· 3 citedOpen Access
SCF <sup>FBXL15</sup> regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1
The EMBO Journal·2011Open Access
SCFFBXL15 regulates BMP signalling by directing the degradation of HECT‐type ubiquitin ligase Smurf1
The EMBO Journal·2011· 60 citedOpen Access
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Frequent Co-authors

Fuchu He(42), Lingqiang Zhang(30), Chunyan Tian(14), Kefeng Lu(12), Handong Wei(10), Ping Xie(9), Chenggang Zhang(8), Yuxin Yin(7), Li Li(7), Jing Nie(7), Chutse Wu(7), Xiushan Yin(6), Yunping Zhu(6), Yongtao Yu(5), Yuan Lin(5), Shan He(4), Yu Cui(4), Juntao Yang(4), Huipeng Chen(4), Jian Wang(4)