Ken-ichiro Kosai

Kagoshima University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.7kcitations83works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Virus-based gene therapy research(17), Cardiac Fibrosis and Remodeling(14), Liver physiology and pathology(12), Pluripotent Stem Cells Research(10), Tissue Engineering and Regenerative Medicine(9)

Publications83 total

Triple-regulated conditionally replicating adenovirus for effective and safer treatment of peritoneal carcinomatosis
Biochemical and Biophysical Research Communications·2024Open Access
The originally developed oncolytic viruses and gene therapies: From basic research to nonclinical and clinical development
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2022Open Access
Adenovirus Biology, Recombinant Adenovirus, and Adenovirus Usage in Gene Therapy
Viruses·2021· 101 citedOpen Access
Optimization of adenoviral gene transfer in human pluripotent stem cells
Biochemical and Biophysical Research Communications·2021· 3 cited
Safe and low-dose but therapeutically effective adenovirus-mediated hepatocyte growth factor gene therapy for type 1 diabetes in mice
Life Sciences·2021· 10 citedOpen Access
Survivin-responsive conditionally replicating adenovirus for patients with advanced sarcoma demonstrated potent and long-term efficacy and high safety in a phase I clinical trial.
Journal of Clinical Oncology·2020
A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphoma
BMC Cancer·2019· 9 citedOpen Access
Abstract CT122: Phase I study of potentially "best-in-class" survivin-responsive conditionally replicating adenovirus for advanced sarcoma actually demonstrates potent and long-term efficacy and high safety
Cancer Research·2018
Pathogenesis of Lung Injury in Mecp2-null Mouse Model for Rett Syndrome
2017
A Novel Construction of Lentiviral Vectors for Eliminating Tumorigenic Cells from Pluripotent Stem Cells
Stem Cells·2017· 13 citedOpen Access
Pathogenesis of Lethal Aspiration Pneumonia in Mecp2-null Mouse Model for Rett Syndrome
Scientific Reports·2017· 20 citedOpen Access
Viral Vector-Based Innovative Approaches to Directly Abolishing Tumorigenic Pluripotent Stem Cells for Safer Regenerative Medicine
Molecular Therapy — Methods & Clinical Development·2017· 18 citedOpen Access
Original gene therapy and viral vectors to achieve innovative cancer gene-viro-therapy and novel anti-tumorigenic strategies in stem cell-based regenerative medicine
The Molecular Biology Society of Japan·2016
A Novel Construction of Lentiviral Vectors that Identify and Specifically Eliminate Tumorigenic Cells in Pluripotent Stem Cells
The Molecular Biology Society of Japan·2016
Conditionally replicating adenovirus kills tumorigenic pluripotent stem cells
The Molecular Biology Society of Japan·2016
414. A Novel System to Systematically Analyze Diverse Types of Conditionally Replicating Adenoviruses Expressing Immunostimulatory Genes in Syngenic Hamster Models
Molecular Therapy·2016Open Access
241. An Efficient Construction of Lentiviral Vectors That Identify and Eliminate Tumorigenic Cells in Pluripotent Stem Cells
Molecular Therapy·2016· 1 citedOpen Access
Intravenous Administration of Endothelial Colony-Forming Cells Overexpressing Integrin <i>β</i>1 Augments Angiogenesis in Ischemic Legs
Stem Cells Translational Medicine·2015· 29 citedOpen Access
Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias
Scientific Reports·2015· 35 citedOpen Access
Conditionally replicating adenovirus prevents pluripotent stem cell–derived teratoma by specifically eliminating undifferentiated cells
Molecular Therapy — Methods & Clinical Development·2015· 19 citedOpen Access
page 1 of 5Next →

Frequent Co-authors

Tomoyuki Takahashi(25), Hisayoshi Fujiwara(22), Genzou Takemura(16), Takako Fujiwara(16), Satoshi Nagano(14), Shinya Minatoguchi(13), Masayasu Esaki(11), Kazuko Goto(9), Rumi Maruyama(9), Hideshi Okada(8), Hiroaki Ushikoshi(8), Kentaro Yuge(7), Toyojiro Matsuishi(6), Hiromitsu Kanamori(6), Shusaku Miyata(5), Masamichi Kojiro(5), Setsuro Komiya(5), Kaoru Mitsui(5), Kanako Ide(5), Takao Kawai(4)