John T. Leith

Medicine · Health Sciences

33h-index3.2kcitations181works0.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Effects of Radiation Exposure(39), Radiation Therapy and Dosimetry(38), Cancer, Hypoxia, and Metabolism(26), Mathematical Biology Tumor Growth(21), Advanced Radiotherapy Techniques(16)

Publications181 total

Radioresistance of cancer cells, integrin αvβ3 and thyroid hormone
Oncotarget·2018· 27 citedOpen Access
Activation of tumor cell integrin αvβ3 by radiation and reversal of activation by chemically modified tetraiodothyroacetic acid (tetrac)
Endocrine Research·2018· 20 cited
<i>In vitro</i> effects of tetraiodothyroacetic acid combined with X-irradiation on basal cell carcinoma cells
Cell Cycle·2017· 13 citedOpen Access
Actions of Nanoparticulate Tetraiodothyroacetic Acid Nanotetrac on Human Prostate Carcinoma Xenograft Growth Vascularity and Integrin Response to Radiation
Bursa Uludag University - AVESIS·2016
Corrigendum: “Cancer Cell Gene Expression Modulated from Plasma Membrane Integrin αvβ3 by Thyroid Hormone and Nanoparticulate Tetracâ€
Frontiers in Endocrinology·2015· 5 citedOpen Access
Combined Radiation-Adriamycin Effects on Human Skin
Frontiers of radiation therapy and oncology·2015· 13 cited
Cancer Cell Gene Expression Modulated from Plasma Membrane Integrin αvβ3 by Thyroid Hormone and Nanoparticulate Tetrac
Frontiers in Endocrinology·2015· 94 citedOpen Access
Abstract 5378: Actions of nanoparticulate tetraiodothyroacetic acid (Nanotetrac) on human prostate carcinoma xenograft growth, vascularity and integrin response to radiation
Cancer Research·2014· 2 cited
Nanotetrac targets integrin &amp;alpha;v&amp;beta;3 on tumor cells to disorder cell defense pathways and block angiogenesis
OncoTargets and Therapy·2014· 43 citedOpen Access
Tetraiodothyroacetic acid (tetrac) receptor on integrin αvβ3: tetrac blocks activation of the integrin response to tumor cell irradiation (974.6)
The FASEB Journal·2014
Abstract 3447: Tetrac (tetraiidothyroacetic acid) decreases in vitro x-ray survival of a human medullary thyroid cancer cell line under oxic and hypoxic conditions
Cancer Research·2012
Abstract 2673: Tetraiodothyroacetic acid (tetrac) produces an increase in the unirradiated steady-state levels of DNA double strand breaks (DSBs) and inhibition of repair of DSBs after x-irradiation in human U87MG brain tumor cells
Cancer Research·2011
A short account of the settlement, produce, and commerce, of Prince of Wales Island in the Straits of Malacca.
2011· 4 cited
Radiosensitization and production of DNA double-strand breaks in U87MG brain tumor cells induced by tetraiodothyroacetic acid (tetrac)
Cell Cycle·2011· 35 citedOpen Access
Radiosensitization of GL261 glioma cells by tetraiodothyroacetic acid (tetrac)
Cell Cycle·2009· 29 citedOpen Access
Abstract #2309: The effect of tetraiodothyroacetic acid (tetrac) on the in vitro oxygen enhancement ratio of x-irradiated GL261 murine brain tumor cells
Cancer Research·2009
546 POSTER Gl261 brain tumor cells: responses to single or fractionated x-irradiation with the avb3 integrin thyroxine receptor antagonist TETRAC (tetraiodothyroacetic acid)
European Journal of Cancer Supplements·2008
Reactor Dosimetry Study of the Rhode Island Nuclear Science Center
Journal of ASTM International·2006· 1 cited
Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function
Combinatorial Chemistry & High Throughput Screening·2005· 6 cited
Combined thalidomide-radiation effect <i>in vitro</i> study
Journal of Clinical Oncology·2005
page 1 of 10Next →

Frequent Co-authors

Arvin S. Glicksman(10), Daniel L. Dexter(6), S Michelson(6), Eugene W. Gerner(5), Paul J. Davis(5), W. Schilling(5), Seth Michelson(5), Aleck Hercbergs(5), Bernard S. Lewinsky(5), Hung‐Yun Lin(4), Aleck Hercbergs(3), Shaker A. Mousa(3), Carla M. Arundel(3), Sarah F. Bliven(3), Robert C. Miller(2), Max L. M. Boone(2), Heng-Yuan Tang(2), Osnat Ashur‐Fabian(2), Sandra Incerpi(2), Paul Calabresi(2)