John C. Drach

Advanced Animal Diagnostics (United States) — United States

Medicine · Health Sciences

42h-index7.0kcitations300works0.02yr avg
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Research Topics

Cytomegalovirus and herpesvirus research(108), Synthesis and Biological Evaluation(65), Synthesis and Characterization of Heterocyclic Compounds(64), HIV/AIDS drug development and treatment(62), Biochemical and Molecular Research(60)

Publications300 total

Leukocyte dynamics in vaccinated and unvaccinated animals following dual challenge with Bovine Viral Diarrhea Virus-Mannheimia haemolytica model to compare vaccine efficacy in calves
Texas A&M University Libraries·2024Open Access
Targeting the terminase: An important step forward in the treatment and prophylaxis of human cytomegalovirus infections
Antiviral Research·2018· 37 cited
Tetrahalogenated benzimidazole D-ribonucleosides are active against rat cytomegalovirus
Antiviral Research·2016· 15 cited
Human Cytomegalovirus Resistance to Deoxyribosylindole Nucleosides Maps to a Transversion Mutation in the Terminase Subunit-Encoding Gene <i>UL89</i>
Antimicrobial Agents and Chemotherapy·2014· 3 citedOpen Access
Metabolism of Cyclopropavir and Ganciclovir in Human Cytomegalovirus-Infected Cells
Antimicrobial Agents and Chemotherapy·2014· 24 citedOpen Access
Resistance of Human Cytomegalovirus to Cyclopropavir Maps to a Base Pair Deletion in the Open Reading Frame of <i>UL97</i>
Antimicrobial Agents and Chemotherapy·2013· 17 citedOpen Access
Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir
Bioorganic & Medicinal Chemistry·2012· 10 citedOpen Access
Tyrosine-Based 1-(<i>S</i>)-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((<i>S</i>)-HPMPC and (<i>S</i>)-HPMPA) Prodrugs: Synthesis, Stability, Antiviral Activity, and in Vivo Transport Studies
Journal of Medicinal Chemistry·2011· 39 citedOpen Access
Benzimidazole Ribonucleosides: Novel Drug Candidates for the Prevention and Treatment of Cytomegalovirus Diseases
2011· 3 cited
Synthesis, transport and antiviral activity of Ala–Ser and Val–Ser prodrugs of cidofovir
Bioorganic & Medicinal Chemistry Letters·2011· 14 citedOpen Access
Studies on Anti-HSV Activity and Cytotoxicity of Morinda citrifolia L. Noni Leaf
Antiviral Research·2011· 2 cited
Amido tyrosine esters: a promising new approach to antiviral nucleoside phosphonate prodrugs
Antiviral Research·2011· 1 cited
Benzimidazole Analogs Inhibit Human Herpesvirus 6
Antimicrobial Agents and Chemotherapy·2011· 19 citedOpen Access
Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase
Biochemical Pharmacology·2010· 31 cited
Stereoselective Phosphorylation of Cyclopropavir by pUL97 and Competitive Inhibition by Maribavir
Antimicrobial Agents and Chemotherapy·2010· 39 citedOpen Access
Synthesis, Antiviral Activity, and Cytotoxicity of some Novel 2-Phenyl-3-Disubstituted Quinazolin-4(3h)-Ones
International Journal of Drug Design and Discovery·2010
Structure–Activity Relationships of d- and L-analogs of Maribavir and 1-Beta-d-ribofuranosyl-2-bromo-5,6-dichlorobenzimidazole (bdcrb) Against Human Herpesvirus 6
Antiviral Research·2010
Changes in Human Cytomegalovirus Transcriptional Patterns Induced by Antiviral Drugs
Antiviral Research·2010
Stereospecific Phosphorylation of Cyclopropavir by pUL97 and Inhibition by Maribavir
Antiviral Research·2010
Inhibition of Human Immunodeficiency Virus Type 1 by Triciribine Involves the Accessory Protein Nef
Antimicrobial Agents and Chemotherapy·2010· 11 citedOpen Access
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Frequent Co-authors

Leroy B. Townsend(27), Charles Shipman(10), Karen K. Biron(7), Roger G. Ptak(7), Earl R. Kern(7), Steven R. Turk(6), Julie M. Breitenbach(6), Jiří Žemlička(6), George W. Koszalka(5), Mark Underwood(5), Mahmoud Nassiri(5), Sandra H. Smith(5), Yung‐Chi Cheng(5), Linda L. Wotring(4), Richard J. Harvey(3), Steven S. Good(3), Rodrigo V. Devivar(3), Kristjan S. Gudmundsson(3), Gloria Komazin(3), Elizabeth A. Gullen(3)