William Charles Kreisl

Columbia University Irving Medical Center — United States

Medicine · Health Sciences

31h-index4.3kcitations128works4.72yr avg
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Research Topics

Alzheimer's disease research and treatments(47), Dementia and Cognitive Impairment Research(45), Medical Imaging Techniques and Applications(23), Drug Transport and Resistance Mechanisms(17), Neuroinflammation and Neurodegeneration Mechanisms(17)

Publications128 total

Concordance of Biological and Clinical Staging of Alzheimer Disease Pathology in Down Syndrome
JAMA Neurology·2026Open Access
Hallucinations and delusions are associated with elevated tau PET signal independent of age, clinical severity, and amyloid burden
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·2026Open Access
Valacyclovir Treatment of Early Symptomatic Alzheimer Disease
JAMA·2025· 1 citedOpen Access
Sex, education and race/ethnicity have distinct effects on amyloid and tau‐PET status
Alzheimer s & Dementia·2025Open Access
Biomarkers.
Apollo (University of Cambridge)·2025
The tau biomarker cascade is condensed in Down syndrome compared to sporadic Alzheimer's disease
Brain·2025
Inflammatory Alterations and Multidomain Cognition in Alzheimer Disease and Related Dementias
Alzheimer Disease & Associated Disorders·2025Open Access
Tau biology, biomarkers, and therapeutics
Alzheimer s & Dementia Translational Research & Clinical Interventions·2025Open Access
Neuroimaging Compendium of Microglia, Amyloid, Tau, and Neurodegeneration Across Clinical Variants of Alzheimer Disease
Alzheimer Disease & Associated Disorders·2025· 1 citedOpen Access
Preliminary Investigation of Obstructive Sleep Apnea and Alzheimer’s Disease in Down Syndrome
SLEEP·2025· 1 citedOpen Access
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex
Nature Neuroscience·2025· 15 citedOpen Access
Cerebellar ARIA in a Patient With an APP Duplication Treated With Lecanemab (P12-3.001)
Neurology·2025
Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI
Journal of Neuropathology & Experimental Neurology·2025· 4 citedOpen Access
Diagnosis and Epidemiology of Dementia
2025
A comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials
Brain Communications·2025Open Access
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex
JuSER Publikationsportal·2025Open Access
Comparison of reference region stability for longitudinal amyloid PET in Down syndrome
Alzheimer s & Dementia·2024Open Access
Comparison of reference region stability for longitudinal amyloid PET in Down syndrome
Alzheimer s & Dementia·2024Open Access
Microglia density measured by TSPO PET across amyloid positivity and clinical variants
Alzheimer s & Dementia·2024Open Access
Alzheimer <sup>’</sup> s-associated inflammatory alterations mediate tau-associated neurodegeneration in limbic and temporal regions across clinical variants of Alzheimer <sup>’</sup> s disease
2024· 1 citedOpen Access
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Frequent Co-authors

Robert B. Innis(22), Victor W. Pike(18), Sami S. Zoghbi(16), Adam M. Brickman(14), Cheryl L. Morse(12), Masahiro Fujita(8), Kimberly J. Jenko(8), Patrick J. Lao(8), José A. Luchsinger(8), Davangere P. Devanand(7), Yaakov Stern(7), Aubrey S. Johnson(7), Zeljko Tomljanovic(7), Chul Hyoung Lyoo(6), Jeih-San Liow(6), Seonjoo Lee(6), Ira T. Lott(6), Julie C. Price(6), Joseph Snow(5), Qolamreza Razlighi(5)