George Sachs

Brown University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

83h-index27.3kcitations646works0.02yr avg
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Research Topics

Ion Transport and Channel Regulation(227), Helicobacter pylori-related gastroenterology studies(194), Gastroesophageal reflux and treatments(73), ATP Synthase and ATPases Research(65), Pancreatic function and diabetes(64)

Publications636 total

Co-occurrence of ipsilateral partial Horner’s syndrome in a patient with monomelic amyotrophy
BMJ Case Reports·2025
The Louise Wilcox ALS Clinic at Rhode Island Hospital: 25th Anniversary (1999-2024).
PubMed·2024
Usability and feasibility of a cognitive-behavioral mobile app for ADHD in adults
PLOS Digital Health·2022· 18 citedOpen Access
Cancer and Peripheral Nerve Disease
Clinics in Geriatric Medicine·2021· 8 cited
Autoimmune Neuropathies
Current clinical neurology·2019
pH-dependent gating mechanism of the <i>Helicobacter pylori</i> urea channel revealed by cryo-EM
Science Advances·2019· 32 citedOpen Access
CryoEM structure of Helicobacter pylori urea channel in closed state
2019
Editorial: control of acid secretion
Alimentary Pharmacology & Therapeutics·2018· 1 citedOpen Access
Measurement of Internal pH in Helicobacter pylori by Using Green Fluorescent Protein Fluorimetry
Journal of Bacteriology·2018· 8 cited
Acid‐regulated gene expression of <i>Helicobacter pylori</i>: Insight into acid protection and gastric colonization
Helicobacter·2018· 35 cited
Treatment of Peptic Ulcer Disease: Yesterday, today and tomorrow
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2018Open Access
The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors
Scientific Reports·2017· 22 citedOpen Access
PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99
2017
Antagonistic Relationship between Na,K‐ATPase αβ Heterodimers and FXYD5 in the Regulation of the Epithelial Integrity
The FASEB Journal·2017
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): Clinical Features, Diagnosis, and Current Treatment Strategies.
PubMed·2016· 23 cited
Selective Assembly of Na,K-ATPase α2β2 Heterodimers in the Heart
Journal of Biological Chemistry·2016· 38 citedOpen Access
The role of acid inhibition in Helicobacter pylori eradication
F1000Research·2016· 69 citedOpen Access
Faculty Opinions recommendation of High-dose dual therapy is superior to standard first-line or rescue therapy for Helicobacter pylori infection.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2016
Faculty Opinions recommendation of Acid-inhibitory effects of vonoprazan 20 mg compared with esomeprazole 20 mg or rabeprazole 10 mg in healthy adult male subjects--a randomised open-label cross-over study.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2016
Faculty Opinions recommendation of Clarithromycin-based standard triple therapy can still be effective for Helicobacter pylori eradication in some parts of the Korea.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2016
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Frequent Co-authors

David R. Scott(11), Jai Moo Shin(8), David L. Weeks(8), Klaus Melchers(7), Elizabeth A. Marcus(6), B. Wallmark(5), G. Saccomani(5), Keith Munson(5), Olga Vagin(5), E. Rabon(4), Christian Prinz(4), Yi Wen(4), T. Berglindh(3), H. H. Chang(3), S. J. Hersey(3), H. F. Helander(3), M Lewin(2), Carin Briving(2), Iskandar Yakubov(2), Nils Lambrecht(2)