S. Locarnini

Medicine · Health Sciences

9h-index594citations54works0.02yr avg
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Research Topics

Hepatitis B Virus Studies(47), Hepatitis C virus research(35), Liver Disease Diagnosis and Treatment(20), HIV/AIDS drug development and treatment(7), Hepatitis Viruses Studies and Epidemiology(6)

Publications54 total

Effects of SB9200 (Inarigivir) therapy on immune responses in patients with chronic hepatitis B
Journal of Hepatology·2018· 9 cited
RNA interference therapy with ARC-520 Injection results in long term off-therapy antigen reductions in treatment naïve, HBeAg positive and negative patients with chronic HBV
Journal of Hepatology·2018· 8 cited
Dose response and safety of the daily, oral RIG-I agonist Inarigivir (SB 9200) in treatment naïve patients with chronic hepatitis B: results from the 25mg and 50mg cohorts in the ACHIEVE trial
Journal of Hepatology·2018· 15 cited
Molecular epidemiology of hepatitis B and D in the Pacific Islands of Kiribati
Journal of Hepatology·2018
On-treatment ALT flares are associated with HBsAg loss in genotype A chronic hepatitis B-infected patients treated with nucleotide analogue therapy
Journal of Hepatology·2017
Durability of HBsAg loss with nucleotide analogs and pegylated interferon in patients infected with hepatitis B virus
Journal of Hepatology·2017· 1 cited
A phase 1 study to evaluate safety and tolerability of escalating single doses of the hepatitis B virus RNA interference drug ARC-521 in a healthy volunteer population
Journal of Hepatology·2017· 9 citedOpen Access
Whole-genome deep sequencing of hepatitis B virus in chronic hepatitis B patients reveals single nucleotide variants associated with baseline HBV DNA levels and HBeAg status
Journal of Hepatology·2017· 3 cited
On-treatment decline in HBeAg level at week 24 predicts for HBeAg seroconversion during long-term tenofovir therapy for HBeAg-positive CHB
Journal of Hepatology·2017
International coalition to eliminate hepatitis B - progress report
Journal of Hepatology·2017
Treatment of Chronically HBV-Infected Chimpanzees with RNA Interference Therapeutic ARC-520 LED to Potent Reduction of Viral MRNA, DNA and Proteins without Observed Drug Resistance
Journal of Hepatology·2016· 11 cited
The Presence of BCP/PC Variants Reduces the Rate of HBsAg Loss among HBeAg-Positive CHB Patients Treated with Long-Term Tenofovir DF Therapy
Journal of Hepatology·2016
Controlling viral hepatitis: Public policy lessons from Taiwan
Journal of Clinical Virology·2015
P1048 NUCLEOS(T)IDE ANALOGUE (NA) THERAPY FOR PERSONS IN THE IMMUNOTOLERANT PHASE OF CHB IS ASSOCIATED WITH SIGNIFICANT DECLINE IN HBeAg AND HBsAg LEVELS
Journal of Hepatology·2014
P653 RECLASSIFICATION OF IMMUNOTOLERANT CHRONIC HEPATITIS B INFECTION; DETECTION OF HBV VARIANTS WITH IMPLICATIONS FOR HBV DNA, HBsAg AND HBeAg LEVELS
Journal of Hepatology·2014· 1 cited
P672 HBeAg LEVELS DIFFER ACCORDING TO HBV GENOTYPE IN IMMUNE CLEARANCE DISEASE
Journal of Hepatology·2014
463 CLINICAL OUTCOMES, VIROLOGICAL CHANGES AND FLARES IN WOMEN WITH CHRONIC HEPATITIS B VIRUS INFECTION DURING PREGNANCY AND POST PARTUM
Journal of Hepatology·2012
53 TLR2 AND TLR7/8 ACTIVATION PREDICT POST PARTUM HBV FLARES
Journal of Hepatology·2012
SOTA4 Molecular genesis of drug resistant HBV
International Journal of Infectious Diseases·2011Open Access
736 LAMIVUDINE IN LATE PREGNANCY FOR PREVENTION OF HBV TRANSMISSION: EFFECTIVENESS AND DETECTION OF ANTIVIRAL RESISTANCE
Journal of Hepatology·2011· 8 cited
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Frequent Co-authors

S. Bowden(12), Peter Revill(7), Angeline Bartholomeusz(6), Timothy J. Shaw(6), Margaret Littlejohn(6), Lilly Yuen(6), Sharon R. Lewin(6), Anuj Gaggar(6), Kathryn M. Kitrinos(5), A. Thompson(5), R. Hammond(4), Edward Gane(4), A. Ayres(4), Mani Subramanian(4), Peter Angus(3), Danni Colledge(3), K. Jackson(3), Robert G. Gish(3), Ros Edwards(3), Patrick Marcellin(3)