E. A. de Bruijn

London Clinic — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

34h-index6.1kcitations163works0.02yr avg
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Research Topics

Cancer therapeutics and mechanisms(24), Chemotherapy-induced organ toxicity mitigation(16), Colorectal Cancer Treatments and Studies(13), Angiogenesis and VEGF in Cancer(12), Drug Transport and Resistance Mechanisms(11)

Publications160 total

The Nitrogen Mustards
Pharmacological Reviews·2022· 56 citedOpen Access
The Neurotoxicity and Pharmacokinetics of Oral Ifosfamide
Journal of Analytical Oncology·2015· 8 citedOpen Access
The αVβ3/αVβ5 integrin inhibitor cilengitide augments tumor response to melphalan isolated limb perfusion in a sarcoma model
International Journal of Cancer·2012· 11 cited
Interaction of Imatinib with Human Organic Ion Carriers
Clinical Cancer Research·2008· 228 citedOpen Access
Celecoxib inhibits growth of tumors in a syngeneic rat liver metastases model for colorectal cancer
Cancer Chemotherapy and Pharmacology·2008· 16 citedOpen Access
Isolated Hypoxic Hepatic Perfusion with Retrograde Outflow in Patients with Irresectable Liver Metastases; A New Simplified Technique in Isolated Hepatic Perfusion
Annals of Surgical Oncology·2008· 23 citedOpen Access
Docetaxel and gemcitabine combination therapy in advanced transitional cell carcinoma of the urothelium: results of a phase II and pharmacologic study
Anti-Cancer Drugs·2006· 22 cited
Simultaneous determination of AMN107 and Imatinib (Gleevec®, Glivec®, STI571) in cultured tumour cells using an isocratic high-performance liquid chromatography procedure with UV detection
Journal of Chromatography B·2006· 19 cited
Early destruction of tumor vasculature in tumor necrosis factor-α-based isolated limb perfusion is responsible for tumor response
Anti-Cancer Drugs·2006· 38 cited
Modified Approach of Administering Cytostatics to the Lung: More Efficient Isolated Lung Perfusion
The Annals of Thoracic Surgery·2006· 5 citedOpen Access
Decreased response rates by the combination of histamine and IL-2 in melphalan-based isolated limb perfusion
Cancer Immunology Immunotherapy·2006· 9 citedOpen Access
Everolimus alters imatinib blood partition in favour of the erythrocyte
Journal of Pharmacy and Pharmacology·2006· 13 citedOpen Access
Recent applications of liquid chromatography–mass spectrometry in forensic science
Journal of Chromatography A·2006· 118 cited
The Pharmacokinetics of Mitomycin C in the Mitomycin C, Ifosfamide and Cisplatin (MIC) Regimen
International Journal of Pharmacology·2006· 3 cited
A phase I dose-finding clinical pharmacokinetic study of an oral formulation of irinotecan (CPT-11) administered for 5 days every 3 weeks in patients with advanced solid tumours
Annals of Oncology·2006· 19 cited
Imatinib (Gleevec®, Glivec®) tumour tissue analysis by measurement of sediment and by liquid chromatography tandem mass spectrometry
Journal of Separation Science·2006· 11 cited
Proteomics in cancer research: Methods and application of array-based protein profiling technologies
Analytica Chimica Acta·2005· 15 cited
In vitro partition of irinotecan (CPT-11) in human volunteer blood: the influence of concentration, gender and smoking
Anti-Cancer Drugs·2005· 12 cited
In vitro partition of docetaxel and gemcitabine in human volunteer blood: the influence of concentration and gender
Anti-Cancer Drugs·2005· 12 cited
Balloon catheter hypoxic pelvic perfusion with mitomycin C and melphalan for locally advanced tumours in the pelvic region: A phase I—II trial
European Journal of Surgical Oncology·2005· 9 cited
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Frequent Co-authors

Gert De Boeck(17), A.T. van Oosterom(12), Martin Highley(11), Allan T. van Oosterom(10), R. A. A. Maes(10), Gunther Guetens(7), Alexander M.M. Eggermont(7), Timo L.M. ten Hagen(6), U.R. Tjaden(6), G. Guetens(5), Sandra T. van Tiel(5), Michelle Wood(5), K. Van Cauwenberghe(5), Nele Samyn(4), Bart Landuyt(3), Hans Wildiers(3), Marleen Laloup(3), Michael Morris(3), U. R. Tjaden(3), Marc G. A. van Ijken(3)