Jeffrey C. Theiss

Agouron Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index1.9kcitations70works0.02yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(34), DNA Repair Mechanisms(14), Safe Handling of Antineoplastic Drugs(12), Effects and risks of endocrine disrupting chemicals(9), Indoor Air Quality and Microbial Exposure(5)

Publications70 total

Increase in thyroid follicular cell tumors in nelfinavir-treated rats observed in a 2-year carcinogenicity study is consistent with a rat-specific mechanism of thyroid neoplasia
Human & Experimental Toxicology·2005· 18 cited
NMR of biofluids and pattern recognition: assessing the impact of NMR parameters on the principal component analysis of urine from rat and mouse
Journal of Pharmaceutical and Biomedical Analysis·2001· 81 cited
Use of acridine orange in: flow cytometric assessment of micronuclei induction
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·1998· 49 cited
Use of acridine orange in: flow cytometric evaluation of erythropoietic cytotoxicity
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·1998· 29 cited
Functional and subcellular organelle changes in isolated rat and human hepatocytes induced by tetrahydroaminoacridine
Archives of Toxicology·1998· 16 cited
Principles and practices of integrating genotoxicity evaluation into routine toxicology studies: A pharmaceutical industry perspective
Environmental and Molecular Mutagenesis·1998· 41 cited
O XIX D.2 Principle and practices for integrating genotoxicity evaluation in routine industrial toxicology studies
Mutation research. Fundamental and molecular mechanisms of mutagenesis·1997· 1 cited
P XIX.8 Development and validation of rat micronucleus (MN) analysis using flow cytometer: A comparison with manual method
Mutation research. Fundamental and molecular mechanisms of mutagenesis·1997
In vitro induction of micronuclei and chromosome aberrations by quinolones: possible mechanisms
Mutation research. Fundamental and molecular mechanisms of mutagenesis·1996· 24 cited
Cytotoxicity Study of Tacrine, Structurally and Pharmacologically Related Compounds Using Rat Hepatocytes
Drug and Chemical Toxicology·1996· 16 cited
Genotoxicity evaluation of selenium sulfide in in vivo and in vivo/in vitro micronucleus and chromosome aberration assays
Mutation Research/Genetic Toxicology·1996· 26 cited
Preclinical toxicology studies with the angiotensin-converting enzyme inhibitor quinapril hydrochloride (accupril).
The Journal of Toxicological Sciences·1996· 4 citedOpen Access
Comparison of Tacrine-Induced Cytotoxicity in Primary Cultures of Rat, Mouse, Monkey, Dog, Rabbit, and Human Hepatocytes
Drug and Chemical Toxicology·1996· 16 cited
Use of cyclophosphamide as a positive control in dominant lethal and micronucleus assays
Mutation Research/Environmental Mutagenesis and Related Subjects·1995· 38 cited
Simultaneous evaluation of dexamethasone-induced apoptosis and micronuclei in rat primary spleen cell cultures
Mutation research. Fundamental and molecular mechanisms of mutagenesis·1995· 22 cited
An in vivo/in vitro method for assessing micronucleus and chromosome aberration induction in rat bone marrow and spleen 1. Studies with cyclophosphamide
Mutation Research/Environmental Mutagenesis and Related Subjects·1995· 46 cited
An in vivo/in vitro method for assessing micronucleus and chromosome aberration induction in rat bone marrow and spleen 2. Studies with chlorambucil and mitomycin C
Mutation Research/Environmental Mutagenesis and Related Subjects·1995· 11 cited
The genotoxicity profile of atorvastatin, a new drug in the treatment of hypercholesterolemia
Mutation Research/Genetic Toxicology·1995· 27 cited
Concurrent analysis of cytogenetic damage in vivo: A multiple endpoint‐multiple tissue approach
Environmental and Molecular Mutagenesis·1995· 27 cited
Mammalian cell gene mutation assays working group report
Mutation Research/Environmental Mutagenesis and Related Subjects·1994· 63 cited
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Frequent Co-authors

G. Krishna(15), Thomas S. Matney(11), Thomas H. Connor(9), G. Urda(9), Michael B. Shimkin(7), David Monteith(6), Roger W. Anderson(5), Melvin L. Kropko(5), Gary D. Stoner(4), Jana L. Laidlaw(4), Tot V. Nguyen(3), Fang Moore(3), Victor Ciaravino(3), Cham E. Dallas(3), Ronald D. Fiedler(3), William H. Puckett(2), William J. Dana(2), Gregory J. Stevens(2), Lionel A. Poirier(2), Lyle J. Arnold(2)