Helen J. Blair

APC Microbiome Institute — Ireland

Medicine · Health Sciences

22h-index2.4kcitations89works7.52yr avg
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Research Topics

Acute Lymphoblastic Leukemia research(25), Acute Myeloid Leukemia Research(21), Epigenetics and DNA Methylation(9), Chronic Myeloid Leukemia Treatments(9), Animal Genetics and Reproduction(8)

Publications89 total

Correction: Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Cancer Cell International·2025Open Access
Perinatal maternal microbiota disruption leads to changes in blood-cerebrospinal fluid barrier integrity
Neuroscience Applied·2025Open Access
MDB-74. SERINE/GLYCINE METABOLISM REPRESENTS A NOVEL TARGETABLE THERAPEUTIC VULNERABILITY IN MYC-AMPLIFIED MEDULLOBLASTOMA
Neuro-Oncology·2024Open Access
Combination p53 activation and BCL-xL/BCL-2 inhibition as a therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Leukemia·2024· 13 citedOpen Access
Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth
Nature Communications·2024· 29 citedOpen Access
Fusion transcripts are present in early progenitor cells in KMT2A-rearranged B-ALL
Leukemia·2024· 3 citedOpen Access
Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Cancer Cell International·2023· 5 citedOpen Access
Leukemic stem cells hijack lineage inappropriate signalling pathways to promote their growth
2023· 2 citedOpen Access
Disruption to the FOXO-PRDM1 axis resulting from deletions of chromosome 6 in acute lymphoblastic leukaemia
Leukemia·2023· 5 citedOpen Access
Biallelic TET2 mutations confer sensitivity to 5′-azacitidine in acute myeloid leukemia
JCI Insight·2022· 9 citedOpen Access
Dual Targeting of MDM2 and BCL2/Bclxl Demonstrates Potent Synergistic Activity in High-Risk Adult Acute Lymphoblastic Leukemia
Blood·2022
A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia
Journal of Medicinal Chemistry·2022· 11 citedOpen Access
hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia
Cell Reports Medicine·2022· 19 citedOpen Access
Synthesis and <i>In Vivo</i> Evaluation of a Site-specifically Labeled Radioimmunoconjugate for Dual-Modal (PET/NIRF) Imaging of MT1-MMP in Sarcomas
Bioconjugate Chemistry·2022· 20 citedOpen Access
Epigenetic regulator genes direct lineage switching in  <i>MLL/AF4</i> leukemia
Blood·2022· 64 citedOpen Access
The development of a dual-modality (PET/NIR) radioimmunoconjugate for image-guided sarcoma surgery
Nuclear Medicine and Biology·2022
Ex vivo and in vivo complex drug combination analysis for improved efficacy and specificity in high-risk childhood acute lymphoblastic leukaemia
Klinische Pädiatrie·2022
3113 – LEUKAEMIC STEM CELLS CELL HIJACK LINEAGE INAPPROPRIATE SIGNALLING PATHWAYS TO ACTIVATE GROWTH
Experimental Hematology·2022
An ex vivo human bone marrow milieu identifies CDH2 as a driver of niche-mediated treatment resistance in leukaemia
2021
Biallelic <i>TET2</i> mutation sensitizes to 5’-azacitidine in acute myeloid leukemia
2021Open Access
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Frequent Co-authors

Olaf Heidenreich(21), Yvonne Boyd(15), Josef Vormoor(12), James M. Allan(9), Sirintra Nakjang(9), Constanze Bonifer(7), Simon Bomken(7), Ricky Tirtakusuma(7), Salam A. Assi(6), Anetta Ptasinska(6), Paulynn Suyin Chin(6), Peter N. Cockerill(6), Vivienne Reed(6), Steven H. Laval(6), Julie Irving(5), Christina Halsey(5), Christine J. Harrison(5), Sandeep Potluri(5), Natalia Martinez-Soria(5), Deepali Pal(5)