J. D. Chapman

Biochemistry, Genetics and Molecular Biology · Life Sciences

42h-index4.5kcitations105works0.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(38), Radiation Therapy and Dosimetry(18), Effects of Radiation Exposure(18), Nanoplatforms for cancer theranostics(17), Photodynamic Therapy Research Studies(12)

Publications105 total

Can the two mechanisms of tumor cell killing by radiation be exploited for therapeutic gain?
Journal of Radiation Research·2013· 28 citedOpen Access
The Power of Radiation Biophysics—Let's Use It
International Journal of Radiation Oncology*Biology*Physics·2012· 27 cited
<i>In vivo</i> 19F Magnetic Resonance Spectroscopy and Chemical Shift Imaging of Tri-Fluoro-Nitroimidazole as a Potential Hypoxia Reporter in Solid Tumors
Clinical Cancer Research·2007· 55 cited
In response to Dr. Wang et al.
International Journal of Radiation Oncology*Biology*Physics·2004· 4 cited
Radiosensitization of tumour cells by cantharidin and some analogues
International Journal of Radiation Biology·2004· 17 cited
In response to Dr. Orton
International Journal of Radiation Oncology*Biology*Physics·2004· 5 cited
Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning
European Journal of Nuclear Medicine and Molecular Imaging·2003· 92 cited
Incorporating clinical measurements of hypoxia into tumor local control modeling of prostate cancer: Implications for the α/β ratio
International Journal of Radiation Oncology*Biology*Physics·2003· 213 citedOpen Access
Single-hit mechanism of tumour cell killing by radiation
International Journal of Radiation Biology·2003· 16 cited
Molecular (functional) imaging for radiotherapy applications: an RTOG symposium
International Journal of Radiation Oncology*Biology*Physics·2003· 77 cited
Single-hit mechanism of tumour cell killing by radiation
International Journal of Radiation Biology·2003· 60 cited
Hypoxic prostate/muscle po2 ratio predicts for biochemical failure in patients with prostate cancer: preliminary findings
Urology·2002· 184 cited
The synthesis and radiolabeling of 2-nitroimidazole derivatives of cyclam and their preclinical evaluation as positive markers of tumor hypoxia.
PubMed·2002· 28 cited
Exchange radioiodination produces inversion at C‐4 of 1‐(4‐deoxy‐4‐iodo‐<i>β</i>‐D‐xylopyranosyl)‐2‐nitroimidazole
Journal of Labelled Compounds and Radiopharmaceuticals·2002
The radiation hypersensitivity of cells at mitosis
International Journal of Radiation Biology·2002· 65 cited
A hypoxic ratio of prostate pO2/muscle pO2 predicts for biochemical failure in prostate cancer patients
International Journal of Radiation Oncology*Biology*Physics·2001· 11 cited
On measuring hypoxia in individual tumors with radiolabeled agents.
PubMed·2001· 33 cited
Chromatin Compaction and Tumor Cell Radiosensitivity at 2 Gray
American Journal of Clinical Oncology·2001· 14 cited
Hypoxia in Human Prostate Carcinoma
American Journal of Clinical Oncology·2001· 107 cited
Increased hypoxia correlates with increased expression of the angiogenesis marker vascular endothelial growth factor in human prostate cancer
Urology·2001· 76 cited
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Frequent Co-authors

C. C. Stobbe(18), Gerald E. Hanks(10), Benjamin Movsas(7), Richard E. Greenberg(6), Richard F. Schneider(6), J. Borsa(6), Eric M. Horwitz(5), Alexandra L. Hanlon(5), B. E. Meeker(5), Wayne H. Pinover(4), D.L. Dugle(4), C.J. Gillespie(4), Malcolm S. McPhee(4), A. P. Reuvers(4), Matthew C. Fenning(4), S. Biade(4), Edward L. Engelhardt(3), M.R. Arnfield(3), Özer Algan(3), Renuka Iyer(2)