D. M. JERINA

National Institutes of Health — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

51h-index10.0kcitations203works0.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(51), Eicosanoids and Hypertension Pharmacology(39), Carcinogens and Genotoxicity Assessment(29), Organic Chemistry Cycloaddition Reactions(28), Chemical Reaction Mechanisms(25)

Publications203 total

Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene
Carcinogenesis·2013· 13 citedOpen Access
CCDC 213703: Experimental Crystal Structure Determination
The Cambridge Structural Database·2004Open Access
NMR Evidence for Syn-Anti Interconversion of a Trans Opened (10<i>R</i>)-dA Adduct of Benzo[<i>a</i>]pyrene (7<i>S</i>,8<i>R</i>)-Diol (9<i>R</i>,10<i>S</i>)-Epoxide in a DNA Duplex
Biochemistry·2000· 42 cited
ChemInform Abstract: Catalytic Aminohydroxylation Using Adenine‐Derivatives as the Nitrogen Source.
ChemInform·1998
ChemInform Abstract: Bacterial Dioxygenase‐Catalyzed Dihydroxylation and Chemical Resolution Routes to Enantiopure cis‐Dihydrodiols of Chrysene.
ChemInform·1997· 2 cited
Solution Structure of the Minor Conformer of a DNA Duplex Containing a dG Mismatch Opposite a Benzo[<i>a</i>]pyrene Diol Epoxide/dA Adduct:  Glycosidic Rotation from Syn to Anti at the Modified Deoxyadenosine
Biochemistry·1997· 36 cited
Kinetics and mechanism of autoprocessing of human immunodeficiency virus type 1 protease from an analog of the Gag-Pol polyprotein.
Proceedings of the National Academy of Sciences·1994· 97 cited
ChemInform Abstract: Synthesis and Solvolysis of Acridine 1,2‐ and 3,4‐Oxides: Crystal Structure of Acridine 1,2‐Oxide.
ChemInform·1994
Mutagenic selectivity at the <i>HPRT</i> locus in V-79 cells: comparison of mutations caused by bay-region benzo[<i>a</i>]pyrene 7,8-diol-9,10-epoxide enantiomers with high and low carcinogenic activity
Carcinogenesis·1994· 59 cited
ChemInform Abstract: Methanolysis of K‐Region Arene Oxides: Comparison Between Acid‐ Catalyzed and Methoxide Ion Addition Reactions.
ChemInform·1993· 1 cited
ChemInform Abstract: Acid‐Catalyzed Rearrangement of K‐Region Arene Oxides: Observation of Ketone Intermediates and a Sterically Induced Change in Rate‐ Determining Step.
ChemInform·1993
ChemInform Abstract: Synthesis and Spontaneous Racemization of Benz(a)anthracene 3,4‐Oxide: Photochemical Oxygen‐Walk Rearrangements of Arene Oxides of Benz(a) anthracene and Triphenylene to Yield Oxepines.
ChemInform·1993
Mutagenic specificities of four stereoisomeric benzo[c]phenanthrene dihydrodiol epoxides.
Proceedings of the National Academy of Sciences·1992· 39 citedOpen Access
Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.
Proceedings of the National Academy of Sciences·1991· 74 cited
ChemInform Abstract: Solvolysis of K‐Region Arene Oxides: Substituent Effects on Reactions of Benz(a)anthracene 5,6‐Oxide.
ChemInform·1991· 1 cited
Continuous microspectrophotometric measurement of DNA polymerase activity: application to the Klenow fragment of Escherichia coli DNA polymerase I and human immunodeficiency virus type 1 reverse transcriptase.
Proceedings of the National Academy of Sciences·1991· 9 citedOpen Access
ChemInform Abstract: Trapping of a Carbocationic Intermediate in the Spontaneous Hydrolysis Reaction of 7β,8α‐Dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(a)py# rene: Mechanism of the Spontaneous and General Acid Catalyzed Hydrolysis Reactions of Bay‐Region Benzo(a)pyrene 7,8‐Diol 9,10‐Epoxides.
ChemInform·1990· 1 cited
ChemInform Abstract: Synthesis of Arene Oxide and trans‐Dihydrodiol Metabolites of Quinoline.
ChemInform·1990
ChemInform Abstract: Comparative Solvolytic Reactivity of Bay‐Region Diol Epoxides Derived from Dibenz(a,j)anthracene and Dibenzacridines
ChemInform·1990
ChemInform Abstract: Synthesis of Optically Active Fjord‐Region 11,12‐Diol 13,14‐Epoxides and the K‐Region 9,10‐Oxide of the Carcinogen Benzo(g)chrysene.
ChemInform·1990
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Frequent Co-authors

Wayne Levin(29), Allan H. Conney(22), Haruhiko Yagi(21), Alexander W. Wood(16), Dhiren R. Thakker(11), Richard L. Chang(10), John W. Daly(9), Albert Lu(9), Roland E. Lehr(5), Thomas K. H. Chang(5), Óscar Hernández(4), Patrick M. Dansette(4), Jane M. Sayer(4), Dene E. Ryan(4), Franz Oesch(3), Masato Koreeda(3), D. W. Ryan(3), Kamlesh P. Vyas(3), Maria Schaefer-Ridder(3), Jean M. Karle(3)