Pascal Degrace

Inserm — France

Medicine · Health Sciences

27h-index2.3kcitations81works4.82yr avg
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Research Topics

Cannabis and Cannabinoid Research(24), Peroxisome Proliferator-Activated Receptors(23), Diet and metabolism studies(18), Diet, Metabolism, and Disease(15), Fatty Acid Research and Health(14)

Publications81 total

Blockade of cannabinoid CB<sub>1</sub> receptors potentiates the anti‐fibrotic effects mediated by SGLT2 inhibition in a mouse model of diabetic nephropathy
British Journal of Pharmacology·2025· 2 citedOpen Access
A Simplified and Robust Model for the Study of Diabetic Nephropathy: Streptozotocin-Induced Diabetic Mice Fed a High-Protein Diet
International Journal of Molecular Sciences·2025Open Access
Les antagonistes des récepteurs aux cannabinoïdes de type 1 (CB1) à action périphérique ont-ils un avenir dans le traitement de l’obésité et du diabète de type 2 ?
Médecine des Maladies Métaboliques·2024Open Access
Impaired unsaturated fatty acid elongation alters mitochondrial function and accelerates metabolic dysfunction-associated steatohepatitis progression
Metabolism·2024· 17 citedOpen Access
Inhibition of mitochondrial fatty acid β-oxidation activates mTORC1 pathway and protein synthesis via Gcn5-dependent acetylation of Raptor in zebrafish
Journal of Biological Chemistry·2023· 13 citedOpen Access
Therapeutic potential of a novel peripherally restricted CB1R inverse agonist on the progression of diabetic nephropathy
Frontiers in Nephrology·2023· 16 citedOpen Access
MO608: INV-202, A CB1 Receptor Blocker, Reduces Renal Injury in A Murine Model of Streptozotocin (STZ)-Induced Type-1 Diabetes
Nephrology Dialysis Transplantation·2022· 1 cited
Chemical Synthesis, Pharmacokinetic Properties and Biological Effects of JM-00266, a Putative Non-Brain Penetrant Cannabinoid Receptor 1 Inverse Agonist
International Journal of Molecular Sciences·2022· 9 citedOpen Access
Endocannabinoids Produced by White Adipose Tissue Modulate Lipolysis in Lean but Not in Obese Rodent and Human
Frontiers in Endocrinology·2021· 20 citedOpen Access
Liraglutide Increases the Catabolism of Apolipoprotein B100–Containing Lipoproteins in Patients With Type 2 Diabetes and Reduces Proprotein Convertase Subtilisin/Kexin Type 9 Expression
2021Open Access
Liraglutide Increases the Catabolism of Apolipoprotein B100–Containing Lipoproteins in Patients With Type 2 Diabetes and Reduces Proprotein Convertase Subtilisin/Kexin Type 9 Expression
Diabetes Care·2021· 50 citedOpen Access
Liraglutide Increases the Catabolism of Apolipoprotein B100–Containing Lipoproteins in Patients With Type 2 Diabetes and Reduces Proprotein Convertase Subtilisin/Kexin Type 9 Expression
2021· 1 citedOpen Access
Simultaneous inhibition of peripheral CB1R and iNOS mitigates obesity-related dyslipidemia through distinct mechanisms
2020Open Access
Simultaneous inhibition of peripheral CB1R and iNOS mitigates obesity-related dyslipidemia through distinct mechanisms
2020Open Access
Simultaneous Inhibition of Peripheral CB1R and iNOS Mitigates Obesity-Related Dyslipidemia Through Distinct Mechanisms
Diabetes·2020· 20 citedOpen Access
Mitochondrial Fatty Acid β-Oxidation Inhibition Promotes Glucose Utilization and Protein Deposition through Energy Homeostasis Remodeling in Fish
Journal of Nutrition·2020· 71 citedOpen Access
Endocannabinoids: the lipid effectors of metabolic regulation in health and disease
Elsevier eBooks·2020· 2 cited
Contributors
Elsevier eBooks·2020
Functional differences between<scp>l</scp>- and<scp>d</scp>-carnitine in metabolic regulation evaluated using a low-carnitine Nile tilapia model
British Journal Of Nutrition·2019· 37 citedOpen Access
Orosensory Detection of Dietary Fatty Acids Is Altered in CB1R−/− Mice
Nutrients·2018· 22 citedOpen Access
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Frequent Co-authors

Laurent Demizieux(23), Joseph Gresti(21), Pierre Clouet(15), Zhen‐Yu Du(14), Tony Jourdan(11), Bruno Vergès(11), Jean-Paul Paı̈s de Barros(6), Tania Muller(6), Louiza Djaouti(5), Jean‐Michel Chardigny(5), Julia Leemput(5), Patricia Passilly‐Degrace(5), Lixia Tian(4), Isabelle Niot(4), Philippe Besnard(4), Samwel Mchele Limbu(4), Mei‐Ling Zhang(4), Bastien Moindrot(4), S. Troy-Fioramonti(4), Chloé Buch(4)