Hitoshi Matsushime

Astellas Pharma (Japan) — Japan

Medicine · Health Sciences

22h-index5.4kcitations31works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(11), Epigenetics and DNA Methylation(6), Receptor Mechanisms and Signaling(4), Microtubule and mitosis dynamics(3), Ion channel regulation and function(3)

Publications31 total

TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells
Proceedings of the National Academy of Sciences·2009· 397 citedOpen Access
The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia
Proceedings of the National Academy of Sciences·2008· 79 citedOpen Access
YM753, a novel histone deacetylase inhibitor, exhibits antitumor activity with selective, sustained accumulation of acetylated histones in tumors in the WiDr xenograft model
International Journal of Oncology·2008· 40 citedOpen Access
Diabetic modifier QTLs in F2 intercrosses carrying homozygous transgene of TGF-β
Mammalian Genome·2007· 4 cited
Regulation of <i>CYL</i> /Cyclin D Genes by Colony‐Stimulating Factor 1
Novartis Foundation symposium·2007· 24 cited
Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2
Proceedings of the National Academy of Sciences·2006· 288 citedOpen Access
Corrigendum to “Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor” [Biochem. Biophys. Res. Commun. 326 (2005) 744–751]
Biochemical and Biophysical Research Communications·2005· 2 cited
Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor
Biochemical and Biophysical Research Communications·2004· 373 cited
A Novel Two-pore Domain K+ Channel, TRESK, Is Localized in the Spinal Cord
Journal of Biological Chemistry·2003· 153 citedOpen Access
Molecular identification of nicotinic acid receptor
Biochemical and Biophysical Research Communications·2003· 314 cited
Molecular cloning and characterization of prokineticin receptors
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression·2002· 203 cited
Molecular cloning and characterization of Kv6.3, a novel modulatory subunit for voltage‐gated K<sup>+</sup> channel Kv2.1<sup>1</sup>
FEBS Letters·2002· 53 citedOpen Access
Functional Characterization of Cysteinyl Leukotriene CysLT2 Receptor on Human Coronary Artery Smooth Muscle Cells
Biochemical and Biophysical Research Communications·2001· 65 cited
Immunocyte Ca <sup>2+</sup> Influx System Mediated by LTRPC2
Science·2001· 438 cited
Rapid Downregulation of Cyclin D1 mRNA and Protein Levels by Ultraviolet Irradiation in Murine Macrophage Cells
Biochemical and Biophysical Research Communications·2001· 34 cited
Cdk4 Activation Is Dependent on the Subunit Rearrangement in the Complexes
Biochemical and Biophysical Research Communications·2000· 10 cited
Direct Interaction of p21 Cyclin-Dependent Kinase Inhibitor with the Retinoblastoma Tumor Suppressor Protein
Biochemical and Biophysical Research Communications·1999· 19 cited
Genomic organization of the flt-1 gene encoding for Vascular Endothelial Growth Factor (VEGF) Receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors
Gene·1998· 89 cited
Inactivation of the Cyclin D-dependent Kinase in the Rat Fibroblast Cell Line, 3Y1, Induced by Contact Inhibition
Journal of Biological Chemistry·1997· 69 citedOpen Access
D-Type Cyclin-Dependent Kinase Activity in Mammalian Cells
Molecular and Cellular Biology·1994· 319 cited
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Frequent Co-authors

Kiyoshi Furuichi(12), Takatoshi Soga(7), Jun Takasaki(7), Masazumi Kamohara(7), Hideki Hiyama(6), Martine F. Roussel(5), Charles J. Sherr(5), Tetsu Saito(5), Mitsuyuki Matsumoto(5), Masato Kobori(5), Masabumi Shibuya(5), Jun‐ya Kato(4), Yorikata Sano(4), Kohei Inamura(4), Akira Miyake(4), Shinobu Mochizuki(4), Takahide Ohishi(4), Shun‐ichiro Matsumoto(4), Hiromichi Yokoi(3), Katsura Nozawa(3)