Kenichi Higashino

Shionogi (Japan) — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index2.0kcitations46works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Protein Kinase Regulation and GTPase Signaling(7), Glycosylation and Glycoproteins Research(7), Metabolomics and Mass Spectrometry Studies(5), Cellular transport and secretion(4), Cancer, Hypoxia, and Metabolism(4)

Publications46 total

Involvement of the vagus nerve in the anorectic effect of monoacylglycerol acyltransferase 2 inhibition in mice
Obesity Science & Practice·2023· 2 citedOpen Access
Tri-antennary tri-sialylated mono-fucosylated glycan of alpha-1 antitrypsin as a non-invasive biomarker for non-alcoholic steatohepatitis: a novel glycobiomarker for non-alcoholic steatohepatitis
Scientific Reports·2020· 26 citedOpen Access
Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues
Analytical Chemistry·2019· 21 cited
Quantifying Protein-Specific N-Glycome Profiles by Focused Protein and Immunoprecipitation Glycomics
Journal of Proteome Research·2019· 15 citedOpen Access
Contribution of synovial macrophages to rat advanced osteoarthritis pain resistant to cyclooxygenase inhibitors
Pain·2018· 79 cited
Identification of unique glycoisoforms of vitamin D-binding protein and haptoglobin as biomarker candidates in hepatocarcinogenesis of STAM mice
Glycoconjugate Journal·2018· 7 cited
Sensitization of transient receptor potential vanilloid 4 and increasing its endogenous ligand 5,6-epoxyeicosatrienoic acid in rats with monoiodoacetate-induced osteoarthritis
Pain·2018· 33 cited
The contribution of macrophage/monocyte to cyclooxygenase-independent pain in advanced osteoarthritis model in rats
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2018Open Access
FMISO accumulation in tumor is dependent on glutathione conjugation capacity in addition to hypoxic state
Annals of Nuclear Medicine·2017· 26 citedOpen Access
Discovery of novel cyclic peptide inhibitors of dengue virus NS2B-NS3 protease with antiviral activity
Bioorganic & Medicinal Chemistry Letters·2017· 45 cited
Decreases in 15-lipoxygenase metabolites in Olmsted syndrome model rats
Journal of Dermatological Science·2016· 8 citedOpen Access
AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells
PLoS ONE·2016· 25 citedOpen Access
Quantitative analysis of total serum glycome in human and mouse
PROTEOMICS·2016· 45 cited
Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent “Pimonidazole” in Hypoxia
PLoS ONE·2016· 32 citedOpen Access
Characterization of the role of sphingomyelin synthase 2 in glucose metabolism in whole-body and peripheral tissues in mice
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2016· 41 cited
Does FMISO-PET really reflect only hypoxia?; accumulation mechanism assessment with imaging mass spectrometry
2016
Imaging Mass Spectrometry Reveals Acyl-Chain- and Region-Specific Sphingolipid Metabolism in the Kidneys of Sphingomyelin Synthase 2-Deficient Mice
PLoS ONE·2016· 32 citedOpen Access
A hybrid strategy using global analysis of oxidized fatty acids and bioconversion by <i>Bacillus circulans</i>
Rapid Communications in Mass Spectrometry·2016· 8 cited
Quantitative GSL-glycome analysis of human whole serum based on an EGCase digestion and glycoblotting method
Journal of Lipid Research·2015· 30 citedOpen Access
The accumulation mechanism of the hypoxia imaging probe “FMISO” by imaging mass spectrometry: possible involvement of low-molecular metabolites
Scientific Reports·2015· 66 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Yoshito Numata(14), Takeshi Yoshioka(13), Hitoshi Arita(9), Yoichi Shimizu(7), Yuji Kuge(7), Jun‐ichi Furukawa(7), Kohji Hanasaki(6), Songji Zhao(6), Yasuro Shinohara(6), Toru Nakano(5), Yasunori Yokota(5), Keiko Kawamoto(5), Kinichi Imura(5), Ichiro Hikita(5), Yoshinari Gahara(5), Akinori Arimura(5), Shingo Sakamoto(5), Takahiko Yamamoto(5), Hisatoshi Hanamatsu(5), Yasuyuki Igarashi(5)