W. A. F. Tompkins

University of Pennsylvania — United States

Immunology and Microbiology · Life Sciences

34h-index3.9kcitations136works0.02yr avg
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Research Topics

HIV Research and Treatment(47), Herpesvirus Infections and Treatments(33), Virus-based gene therapy research(30), Immune Cell Function and Interaction(20), T-cell and B-cell Immunology(18)

Publications136 total

OUTCOMES OF AUTOLOGOUS TRANSPLANT, ALLOGENEIC TRANSPLANT, AND CAR T CELL THERAPY IN TP53 ALTERED MANTLE CELL LYMPHOMA: A MULTI‐INSTITUTION RETROSPECTIVE ANALYSIS
Hematological Oncology·2023Open Access
Role of Cytokines in Feline Retrovirus Diseases and Treatment
2020
Fozivudine Tidoxil as Single-Agent Therapy Decreases Plasma and Cell-Associated Viremia during Acute Feline Immunodeficiency Virus Infection
Journal of Veterinary Internal Medicine·2011· 13 citedOpen Access
CD4+CD25+ T regulatory cells from FIV+ cats induce a unique anergic profile in CD8+lymphocyte targets
Retrovirology·2010· 12 citedOpen Access
CD4 <sup>+</sup> CD25 <sup>+</sup> T Regulatory Cells Inhibit CD8 <sup>+</sup> IFN-γ Production During Acute and Chronic FIV Infection Utilizing a Membrane TGF-β-Dependent Mechanism
AIDS Research and Human Retroviruses·2010· 32 citedOpen Access
CD4+CD25+ regulatory T cells are infected and activated during acute FIV infection
Veterinary Immunology and Immunopathology·2008· 69 citedOpen Access
Transforming Growth Factor-β/Transforming Growth Factor-βRII Signaling May Regulate CD4+CD25+ T-Regulatory Cell Homeostasis and Suppressor Function in Feline AIDS Lentivirus Infection
JAIDS Journal of Acquired Immune Deficiency Syndromes·2008· 25 cited
Lentivirus-induced immune dysregulation
Veterinary Immunology and Immunopathology·2008· 50 citedOpen Access
CD4+CD25+ Regulatory T Cells in Viral Infections
2008· 1 cited
Cloning of feline FOXP3 and detection of expression in CD4+CD25+ regulatory T cells
Veterinary Immunology and Immunopathology·2007· 34 citedOpen Access
FIV as a Model for AIDS Pathogenesis Studies
2007· 6 cited
The role of CD4+CD25+ regulatory T cells in viral infections
Veterinary Immunology and Immunopathology·2005· 49 cited
Different thresholds of T cell activation regulate FIV infection of CD4+CD25+ and CD4+CD25− cells
Virology·2005· 25 cited
Preferential Feline Immunodeficiency Virus (FIV) Infection of CD4<sup>+</sup>CD25<sup>+</sup>T-Regulatory Cells Correlates both with Surface Expression of CXCR4 and Activation of FIV Long Terminal Repeat Binding Cellular Transcriptional Factors
Journal of Virology·2005· 51 citedOpen Access
Feline immunodeficiency virus envelope glycoprotein mediates apoptosis in activated PBMC by a mechanism dependent on gp41 function
Virology·2004· 11 cited
Feline Immunodeficiency Virus Infection Phenotypically and Functionally Activates Immunosuppressive CD4+CD25+ T Regulatory Cells
The Journal of Immunology·2004· 106 citedOpen Access
Spontaneous T cell apoptosis in feline immunodeficiency virus (FIV)-infected cats is inhibited by IL2 and anti-B7.1 antibodies
Veterinary Immunology and Immunopathology·2004· 12 cited
B7+CTLA4+ T cells engage in T–T cell interactions that mediate apoptosis: a model for lentivirus-induced T cell depletion
Veterinary Immunology and Immunopathology·2004· 19 cited
Preferential replication of FIV in activated CD4+CD25+T cells independent of cellular proliferation
Virology·2004· 70 cited
Mechanism of feline immunodeficiency virus envelope glycoprotein-mediated fusion
Virology·2004· 31 cited
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Frequent Co-authors

Mary B. Tompkins(29), Suzanne Kennedy‐Stoskopf(8), Holly L. Jordan(7), William E. Rawls(6), Robert V. English(6), Julie K. Levy(6), Tedd A. Childers(5), Thomas W. Vahlenkamp(4), Douglas H. Gebhard(4), Himanshu Garg(4), Jerry W. Ritchey(4), Anjali Joshi(3), Gregg A. Dean(3), Joseph G. Bucci(3), Angela M. Mexas(2), Jonathan E. Fogle(2), Rance K. Sellon(2), Frederick J. Fuller(2), James B. Rottman(2), Marta E. Bull(2)