Jouko Savolainen

University of Eastern Finland — Finland

Medicine · Health Sciences

20h-index2.9kcitations39works0.02yr avg
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Research Topics

Anesthesia and Pain Management(7), Anesthesia and Sedative Agents(6), Pharmaceutical studies and practices(6), Drug Transport and Resistance Mechanisms(5), Antibiotics Pharmacokinetics and Efficacy(5)

Publications39 total

Chronically Ill Patients’ Experiences with Medication Monitoring and Insights into Patients’ and Healthcare Providers’ Involvement in Medication Monitoring – An Interview Study for Pharmacy Customers
Research in Social and Administrative Pharmacy·2024
The effect of hydroxypropyl-beta-cyclodextrin and sucrose on the sublingual absorption of midazolam in rabbits
European Journal of Pharmaceutics and Biopharmaceutics·2012· 12 cited
Determination of midazolam and 1-hydroxymidazolam from plasma by gas chromatography coupled to methane negative chemical ionization mass spectrometry after sublingual administration of midazolam
Journal of Chromatography B·2011· 19 cited
Design, synthesis and in vitro/in vivo evaluation of orally bioavailable prodrugs of a catechol-O-methyltransferase inhibitor
Bioorganic & Medicinal Chemistry Letters·2010· 19 citedOpen Access
Effect of N-betainate and N-piperazine derivatives of chitosan on the paracellular transport of mannitol in Caco-2 cells
European Journal of Pharmaceutical Sciences·2008· 8 cited
Diclofenac readily penetrates the cerebrospinal fluid in children
British Journal of Clinical Pharmacology·2008· 35 citedOpen Access
How Readily Does Ketorolac Penetrate Cerebrospinal Fluid in Children?
The Journal of Clinical Pharmacology·2008· 20 cited
Prodrug Approaches for CNS Delivery
The AAPS Journal·2008· 167 citedOpen Access
Prodrugs: design and clinical applications
Nature Reviews Drug Discovery·2008· 1.6k cited
Large Neutral Amino Acid Transporter Enables Brain Drug Delivery via Prodrugs
Journal of Medicinal Chemistry·2008· 161 cited
Comparison of the Effects of Deramciclane, Ritanserin and Buspirone on Extracellular Dopamine and Its Metabolites in Striatum and Nucleus Accumbens of Freely Moving Rats
Basic & Clinical Pharmacology & Toxicology·2007· 10 citedOpen Access
Cerebrospinal Fluid Distribution of Ibuprofen After Intravenous Administration in Children
PEDIATRICS·2007· 46 cited
Paracetamol (Acetaminophen) Penetrates Readily Into the Cerebrospinal Fluid of Children After Intravenous Administration
PEDIATRICS·2007· 128 cited
Plasma and Cerebrospinal Fluid Concentrations of Indomethacin in Children After Intravenous Administration
The Journal of Clinical Pharmacology·2006· 29 cited
Cerebrospinal Fluid Distribution of Ketoprofen after Intravenous Administration in Young Children
Clinical Pharmacokinetics·2006· 29 cited
The role of physicochemical properties of entacapone and tolcapone on their efficacy during local intrastriatal administration
European Journal of Pharmaceutical Sciences·2005· 25 cited
Fadolmidine-induced ocular hypotension in normotensive rabbits
Journal of Pharmacy and Pharmacology·2005· 2 citedOpen Access
[The blood-brain barrier is challenging drug development].
PubMed·2005
Inefficient central nervous system delivery limits the use of ibuprofen in neurodegenerative diseases
European Journal of Pharmaceutical Sciences·2004· 40 cited
Synthesis and Characterization of Chitosan <i>N</i>-Betainates Having Various Degrees of Substitution
Macromolecules·2004· 107 cited
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Frequent Co-authors

Tomi Järvinen(13), Marko Lehtonen(11), Jarkko Rautio(10), Markus Forsberg(8), Merja Kokki(7), Merja Laisalmi(6), Hannu Taipale(6), Jukka Leppänen(6), Pekka T. Männistö(6), Anne Mannila(5), Elina Kumpulainen(5), M. Heikkinen(5), Pekka Jarho(5), Jukka Gynther(5), Tapio Nevalainen(4), Kristiina Järvinen(4), Juhani Huuskonen(4), Krista Laine(3), Þorsteinn Loftsson(3), Tycho Heimbach(2)