Nina Mitchell

BioMarin (United States) — United States

Medicine · Health Sciences

9h-index1.0kcitations18works0.02yr avg
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Research Topics

Rheumatoid Arthritis Research and Therapies(7), Hemophilia Treatment and Research(5), Virus-based gene therapy research(4), Lymphoma Diagnosis and Treatment(3), Systemic Lupus Erythematosus Research(3)

Publications18 total

Human liver biopsies from people with hemophilia A who received factor VIII gene transfer with valoctocogene roxaparvovec (AAV5-hFVIII-SQ) show unremarkable histopathology and reveal interindividual variability in transgene production
Journal of Hepatology·2022
Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A
Nature Medicine·2022· 106 citedOpen Access
Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer
Gene Therapy·2021· 5 citedOpen Access
Persistence of haemostatic response following gene therapy with valoctocogene roxaparvovec in severe haemophilia A
Haemophilia·2021· 95 citedOpen Access
Early Phase Clinical Immunogenicity of Valoctocogene Roxaparvovec, an AAV5-Mediated Gene Therapy for Hemophilia A
Molecular Therapy·2020· 71 citedOpen Access
A FIRST-IN-HUMAN FOUR-YEAR FOLLOW-UP STUDY OF DURABLE THERAPEUTIC EFFICACY AND SAFETY OF AAV GENE THERAPY WITH VALOCTOCOGENE ROXAPARVOVEC FOR SEVERE HEMOPHILIA A
Hematology Transfusion and Cell Therapy·2020· 3 citedOpen Access
Efficacy, patient-reported outcomes, and safety of the anti-granulocyte macrophage colony-stimulating factor antibody otilimab (GSK3196165) in patients with rheumatoid arthritis: a randomised, phase 2b, dose-ranging study
The Lancet Rheumatology·2020· 41 citedOpen Access
MRI of the joint and evaluation of the granulocyte–macrophage colony-stimulating factor–CCL17 axis in patients with rheumatoid arthritis receiving otilimab: a phase 2a randomised mechanistic study
The Lancet Rheumatology·2020· 27 cited
Late breaking Abstracts
Haemophilia·2020Open Access
Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A
New England Journal of Medicine·2020· 441 citedOpen Access
OP0228 GSK3196165 AN INVESTIGATIONAL ANTI-GM-CSF MONOCLONAL ANTIBODY, IMPROVES PATIENT REPORTED OUTCOMES IN A PHASE IIB STUDY OF PATIENTS WITH RHEUMATOID ARTHRITIS (RA)
Annals of the Rheumatic Diseases·2019· 4 citedOpen Access
No place for ageism in health care
Nursing Standard·2017
Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial
Annals of the Rheumatic Diseases·2015· 193 citedOpen Access
SAT0226 Tocilizumab (TCZ) as Combination Therapy and as Monotherapy VS Methotrexate (MTX) in MTX-Naive Patients with Early Rheumatoid Arthritis: Patient-Reported Outcomes (PROS) from A Randomized, Placebo-Controlled Trial
Annals of the Rheumatic Diseases·2014· 1 cited
OP0041 Tocilizumab (TCZ) in Combination and Monotherapy Versus Methotrexate (MTX) in MTX-Naive Patients (PTS) with Early Rheumatoid Arthritis (RA): Clinical and Radiographic Outcomes from a Randomised, Placebo-Controlled Trial
Annals of the Rheumatic Diseases·2013· 28 cited
Town Administrator Melvin Kleckner welcomed the Task Force and thanked them for their service. Task Force went over updates to parking meters over the past week. Consensus was that the move to the software used by the City of Cambridge was a great improvement. There was still concern about speed of certain processes and the Brookline Card. Members discussed ways to make meters more accessible, such as outdoor lights.
2011
The antigen induced arthritis model: the relevance of the method of induction to its use as a model of human disease.
PubMed·1986· 26 cited
HLA and the genesis of autoimmune diseases
Medical Hypotheses·1978· 3 cited

Frequent Co-authors

Will Lester(6), Wing Yen Wong(6), John Pasi(5), Savita Rangarajan(5), Glenn F. Pierce(5), Emily Symington(4), Michael Laffan(4), Chris B. Russell(4), Benjamin Kim(4), Bella Madan(3), Gerd R Burmester(3), William F. C. Rigby(3), Ronald van Vollenhoven(3), Sophie Dimonaco(3), Katherine Davy(3), David R. Inman(3), Mark Layton(3), Jatin Patel(3), Didier Saurigny(3), R. Williamson(3)