Dong Cao

Henan University — China

Chemistry · Physical Sciences

13h-index714citations22works0.02yr avg
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Research Topics

Synthesis and biological activity(7), Cancer therapeutics and mechanisms(6), Bioactive Compounds and Antitumor Agents(6), Quinazolinone synthesis and applications(4), Synthesis and Biological Evaluation(4)

Publications22 total

Isoprenylated Flavonoids and 2-Arylbenzofurans from the Root Bark of Morus alba L. and Their Cytotoxic Activity of against HGC27 Cancer Cells
Preprints.org·2023· 2 citedOpen Access
Prevalence of sufficient physical activity among general adult population and sub-populations with chronic conditions or disability in the USA
European Journal of Public Health·2023· 23 citedOpen Access
Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents
European Journal of Medicinal Chemistry·2017· 32 cited
Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors
Journal of Medicinal Chemistry·2016· 110 cited
Synthesis, in vitro and in vivo evaluation of novel substituted N-(4-(2-(4-benzylpiperazin-1-yl)ethoxy)phenyl)-N-methyl-quinazolin-4-amines as potent antitumor agents
Bioorganic & Medicinal Chemistry Letters·2016· 4 cited
Synthesis and Biological Evaluation of Novel Substituted 4‐Anilinoquinazolines as Antitumor Agents
Chemical Biology & Drug Design·2015· 3 cited
Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer
Journal of Medicinal Chemistry·2015· 103 citedOpen Access
Pravastatin protects hyperbaric hyperoxia-induced lung injury via inhibiting inflammation in mice.
PubMed·2015· 1 cited
Anti-arthritis effect of a novel quinazoline derivative through inhibiting production of TNF-α mediated by TNF-α converting enzyme in murine collagen-induced arthritis model
Biochemical and Biophysical Research Communications·2015· 15 cited
Synthesis and Evaluation of Millepachine Amino Acid Prodrugs With Enhanced Solubility as Antitumor Agents
Chemical Biology & Drug Design·2015· 6 cited
Synthesis and Biological Evaluation of Novel Millepachine Derivatives As a New Class of Tubulin Polymerization Inhibitors
Journal of Medicinal Chemistry·2014· 54 cited
Synthesis, structure–activity relationships and biological evaluation of barbigerone analogues as anti-proliferative and anti-angiogenesis agents
Bioorganic & Medicinal Chemistry Letters·2014· 11 cited
Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents
Bioorganic & Medicinal Chemistry·2014· 113 cited
Synthesis and Biological Evaluation of 3-Methyl-5-phenylthieno[2,3-<i>d</i>]pyrimidine-2,4(1<i>H</i>,3<i>H</i>)-dione Derivatives for the Treatment of Diet-Induced Obesity
Chemical and Pharmaceutical Bulletin·2014· 2 citedOpen Access
Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors
Bioorganic & Medicinal Chemistry·2013· 57 cited
Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents
European Journal of Medicinal Chemistry·2013· 40 cited
Semi‐Synthesis and Biological Evaluation of 1,2,3‐Triazole‐Based Podophyllotoxin Congeners as Potent Antitumor Agents Inducing Apoptosis in HepG2 Cells
Archiv der Pharmazie·2012· 13 cited
Design, synthesis, and structure–activity relationship studies of novel millepachine derivatives as potent antiproliferative agents
European Journal of Medicinal Chemistry·2012· 38 cited
Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents
European Journal of Medicinal Chemistry·2012· 27 citedOpen Access
Design, synthesis and biological evaluation of thiazole- and indole-based derivatives for the treatment of type II diabetes
European Journal of Medicinal Chemistry·2012· 59 citedOpen Access
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Frequent Co-authors

Lijuan Chen(17), Liang Ma(15), Zhuang Yang(13), Guangcheng Wang(10), Jinying Chen(8), Aihua Peng(8), Xiaolin Liang(7), Mingli Xiang(7), Yuquan Wei(7), Minghai Tang(6), Fei Peng(6), Fang Wang(5), Yun Sang(5), Jingxiang Qiu(5), Yan Ran(5), Taijin Wang(4), Wenshuang Wu(4), Rong‐Hong Zhang(4), Haoyu Ye(4), Lin He(3)