A. Richard Whorton

Duke Medical Center — United States

Medicine · Health Sciences

45h-index7.0kcitations99works0.02yr avg
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Research Topics

Nitric Oxide and Endothelin Effects(42), Sulfur Compounds in Biology(14), Ion channel regulation and function(11), Inflammatory mediators and NSAID effects(10), Redox biology and oxidative stress(10)

Publications99 total

RhoA inactivation by S-nitrosylation regulates vascular smooth muscle contractive signaling
Nitric Oxide·2018· 30 cited
MEDICAL CONTROL FOR EMTS. King County, Wash., program offers safety net for patients, EMTs and the EMS system.
PubMed·2016· 1 cited
Abstract 256: Accuracy of Manual Shock by Paramedics
Circulation·2014
Direct methods for detection of protein S-nitrosylation
Methods·2013· 36 citedOpen Access
Reaction Based Fluorescent Probes for Hydrogen Sulfide
Organic Letters·2012· 222 citedOpen Access
Identification of protein nitrosothiols using phosphine-mediated selective reduction
Nitric Oxide·2011· 21 citedOpen Access
A 35-Year-Old Pregnant Woman Presenting with Sudden Cardiac Arrest Secondary to Peripartum Cardiomyopathy
Prehospital Emergency Care·2011· 6 cited
Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe
Angewandte Chemie International Edition·2011· 579 cited
Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe
Angewandte Chemie·2011· 105 cited
Reductive Ligation Mediated One-Step Disulfide Formation of <i>S</i>-Nitrosothiols
Organic Letters·2010· 60 cited
Transport rather than diffusion-dependent route for nitric oxide gas activity in alveolar epithelium
Free Radical Biology and Medicine·2010· 16 citedOpen Access
Pulmonary alveolar epithelial uptake of <i>S</i>-nitrosothiols is regulated by L-type amino acid transporter
American Journal of Physiology-Lung Cellular and Molecular Physiology·2008· 26 citedOpen Access
A cystine-cysteine shuttle mediated by xCT facilitates cellular responses to <i>S</i>-nitrosoalbumin
American Journal of Physiology-Cell Physiology·2008· 25 cited
Keap1 modification and nuclear accumulation in response to S-nitrosocysteine
Free Radical Biology and Medicine·2007· 60 citedOpen Access
S‐nitrosothiols inhibit RhoA activation through oxidative modification of cysteine 20 residue
The FASEB Journal·2007
Functional characterization of two <i>S</i>-nitroso-<scp>l</scp>-cysteine transporters, which mediate movement of NO equivalents into vascular cells
American Journal of Physiology-Cell Physiology·2006· 45 cited
Redox Regulation of PTEN by S-Nitrosothiols
Molecular Pharmacology·2005· 98 cited
Identification of Stereoselective Transporters for S-Nitroso-L-cysteine
Journal of Biological Chemistry·2005· 80 citedOpen Access
Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner <i>in vitro</i>, in mice and in a patient with metastatic disease
Molecular Cancer Therapeutics·2004· 170 citedOpen Access
Lipopolysaccharide Stimulates Mitochondrial Biogenesis via Activation of Nuclear Respiratory Factor-1
Journal of Biological Chemistry·2003· 188 citedOpen Access
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Frequent Co-authors

Thomas P. Kennedy(7), Richard S. Kent(7), Claude A. Piantadosi(6), Sukhdev S. Brar(5), John R. Hoidal(5), Barbara J. Buckley(5), Ming Xian(4), Andrew J. Ghio(4), Yu-Ting Xuan(4), Chunrong Liu(3), Anne Sturrock(3), Thomas P. Huecksteadt(3), Jürgen C. Frölich(3), John A. Oates(3), Christine M. Padgett(3), M D Smigel(3), Sheng Li(3), Jia Pan(2), Li Sheng(2), Yu Zhao(2)