Alberto J. Kaumann

Universität Hamburg — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

56h-index9.3kcitations210works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(120), Cardiac electrophysiology and arrhythmias(55), Ion channel regulation and function(38), Pharmacological Effects and Assays(34), Neuroscience and Neuropharmacology Research(32)

Publications209 total

No impact of sex and age on beta‐adrenoceptor‐mediated inotropy in human right atrial trabeculae
Acta Physiologica·2020· 14 cited
Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation
Naunyn-Schmiedeberg s Archives of Pharmacology·2020· 18 citedOpen Access
Normalization of force to muscle cross‐sectional area: A helpful attempt to reduce data scattering in contractility studies?
Acta Physiologica·2018· 10 citedOpen Access
Phosphodiesterase PDE2 activity, increased by isoprenaline, does not reduce β-adrenoceptor-mediated chronotropic and inotropic effects in rat heart
Naunyn-Schmiedeberg s Archives of Pharmacology·2018· 9 cited
The β<sub>3</sub>‐adrenoceptor agonist mirabegron increases human atrial force through β<sub>1</sub>‐adrenoceptors: an indirect mechanism?
British Journal of Pharmacology·2017· 53 citedOpen Access
Cardiostimulant Effects of Mirabegron in Human Atrium and Ventricle In Vitro
Heart Lung and Circulation·2017· 1 cited
In permanent atrial fibrillation, PDE3 reduces force responses to 5‐HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias
British Journal of Pharmacology·2016· 25 citedOpen Access
Inhibitors of phosphodiesterases PDE2, PDE3, and PDE4 do not increase the sinoatrial tachycardia of noradrenaline and prostaglandin PGE1 in mice
Naunyn-Schmiedeberg s Archives of Pharmacology·2015· 7 cited
Arch & Kaumann 1993 part 2 of 3
2015
Arch Kaumann 1993 beta 3 and atypical beta-adrenoceptors
2015
Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation
Proceedings of the National Academy of Sciences·2014· 88 citedOpen Access
Mucosa of murine detrusor impairs β<sub>2</sub>-adrenoceptor-mediated relaxation
Neurourology and Urodynamics·2014· 4 cited
Carvedilol induces greater control of β2- than β1-adrenoceptor-mediated inotropic and lusitropic effects by PDE3, while PDE4 has no effect in human failing myocardium
Naunyn-Schmiedeberg s Archives of Pharmacology·2014· 12 cited
Chronic activation of the low affinity site of β<sub>1</sub>‐adrenoceptors stimulates haemodynamics but exacerbates pressure‐overload cardiac remodelling
British Journal of Pharmacology·2013· 4 citedOpen Access
Mucosa of human detrusor impairs contraction and β‐adrenoceptor‐mediated relaxation
British Journal of Urology·2013· 15 citedOpen Access
<scp>PDE3</scp>, but not <scp>PDE4</scp>, reduces β<sub>1</sub>‐ and β<sub>2</sub>‐adrenoceptor‐mediated inotropic and lusitropic effects in failing ventricle from metoprolol‐treated patients
British Journal of Pharmacology·2013· 55 citedOpen Access
Surprises from a cardiac 5-HT4 TG mouse: spontaneous atrial arrhythmias by endogenous 5-HT of atrial origin? Different mechanism of arrhythmias through 5-HT4 receptors and β-adrenoceptors?
Naunyn-Schmiedeberg s Archives of Pharmacology·2013· 1 citedOpen Access
Phosphodiesterases reduce spontaneous sinoatrial beating but not the ‘fight or flight’ tachycardia elicited by agonists through Gs-protein-coupled receptors
Trends in Pharmacological Sciences·2011· 16 cited
Homology model and docking studies on porcine β2 adrenoceptor: description of two binding sites
Journal of Molecular Modeling·2011· 8 cited
Human atrial β<sub>1L</sub>‐adrenoceptor but not β<sub>3</sub>‐adrenoceptor activation increases force and Ca<sup>2+</sup>current at physiological temperature
British Journal of Pharmacology·2010· 30 citedOpen Access
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Frequent Co-authors

Peter Molenaar(7), Finn Olav Levy(6), Louise Sanders(4), Horst Lemoine(4), Lutz Birnbaumer(4), Kenneth Murray(3), Morris J. Brown(3), Ursula Ravens(3), Sabine Bartel(3), Peter Karczewski(3), Ernst‐Georg Krause(3), Trond Brattelid(3), John R. Blinks(3), Bernhard Ehle(2), James Hall(2), Kylie M. Burrell(2), Donathe Vetter(2), Trond Bach(2), Ane Marit Kvingedal(2), Kurt A. Krobert(2)