Marie‐France Robert

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index2.2kcitations28works45.02yr avg
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Research Topics

Histone Deacetylase Inhibitors Research(11), Protein Degradation and Inhibitors(10), Epigenetics and DNA Methylation(5), Liver physiology and pathology(4), Metabolism and Genetic Disorders(4)

Publications26 total

Data from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>
2023Open Access
Supplementary Table 1 from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>
2023Open Access
Supplementary Table 1 from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>
2023Open Access
Supplementary Table 2 from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>
2023Open Access
Supplementary Table 2 from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>
2023Open Access
Data from MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>
2023Open Access
N-(4-(6,7-Disubstituted-quinolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 50 citedOpen Access
1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1)
Bioorganic & Medicinal Chemistry Letters·2009· 49 citedOpen Access
N-(3-fluoro-4-(2-arylthieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamides: A novel series of dual c-Met/VEGFR2 receptor tyrosine kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 34 citedOpen Access
N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1)
Bioorganic & Medicinal Chemistry Letters·2008· 87 citedOpen Access
Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases
Bioorganic & Medicinal Chemistry Letters·2008· 62 citedOpen Access
MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity <i>in vitro</i> and <i>in vivo</i>
Molecular Cancer Therapeutics·2008· 333 citedOpen Access
4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors
Bioorganic & Medicinal Chemistry Letters·2007· 13 citedOpen Access
Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors
Bioorganic & Medicinal Chemistry Letters·2007· 35 citedOpen Access
N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors
Bioorganic & Medicinal Chemistry Letters·2007· 17 citedOpen Access
Evaluation of antitumor activity, anti-angiogenic activity and pharmacodynamic end points for orally active multi-targeted anti-angiogenic kinase inhibitors targeting c-MET, ron, VEGF and Tie-2 receptors
Cancer Research·2006
Development of Potential Antitumor Agents. Synthesis and Biological Evaluation of a New Set of Sulfonamide Derivatives as Histone Deacetylase Inhibitors
Journal of Medicinal Chemistry·2003· 71 citedOpen Access
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
Nature Genetics·2002· 605 cited
An Essential Role for DNA Methyltransferase DNMT3B in Cancer Cell Survival
Journal of Biological Chemistry·2002· 162 citedOpen Access
Mitochondrial 3-Hydroxy-3-Methylglutaryl-CoA Synthase Deficiency: Clinical Course and Description of Causal Mutations in Two Patients
Pediatric Research·2001· 47 citedOpen Access
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Frequent Co-authors

Jeffrey M. Besterman(17), A. Robert MacLeod(13), Jubrail Rahil(13), Marielle Fournel(11), Pu Yan(11), Marie-Claude Trachy-Bourget(11), Jinru Wang(11), Sylvain Lefèbvre(11), Oscar Moradei(11), Zuomei Li(11), Ann Kalita(10), Aihua Lu(10), Hélène Ste-Croix(9), Jianhong Liu(8), Claire Bonfils(7), Nancy Z. Zhou(7), Jeffrey Gillespie(7), Grant A. Mitchell(7), Hannah Nguyen(7), Arkadii Vaisburg(7)