Philip Avner

European Molecular Biology Laboratory — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index3.6kcitations39works0.02yr avg
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Research Topics

Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities(18), Genomics and Chromatin Dynamics(8), Animal Genetics and Reproduction(7), Cancer-related molecular mechanisms research(6), RNA Research and Splicing(6)

Publications38 total

From X-inactivation to neurodevelopment: CHD8-transcription factors (TFs) competitive binding at regulatory regions of CHD8 target genes can contribute to correct neuronal differentiation
Current Research in Neurobiology·2023· 3 citedOpen Access
Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression
Communications Biology·2021· 18 citedOpen Access
Phase separation drives X-chromosome inactivation: a hypothesis
Nature Structural & Molecular Biology·2019· 135 citedOpen Access
Xist IncRNA forms silencing granules that induce heterochromatin formation and repressive complexes recruitment by phase separation
2018· 8 citedOpen Access
Quantitative predictions of protein interactions with long noncoding RNAs
Nature Methods·2016· 129 cited
LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation
Cell·2016· 11 citedOpen Access
ChIP Analysis of the <i>Xist</i>/<i>Tsix</i> Region in <i>Eif1-</i> and <i>Rent1</i>-Interfered Clones and <i>Tsix</i> mRNA Levels during Differentiation
Figshare·2015Open Access
Xist localization and function: new insights from multiple levels
Genome biology·2015· 188 citedOpen Access
L’héritage de Mary F. Lyon (1925-2014)
médecine/sciences·2015· 5 citedOpen Access
Nucleosome assembly proteins and their interacting proteins in neuronal differentiation
Archives of Biochemistry and Biophysics·2012· 40 cited
Interaction between Nucleosome Assembly Protein 1-like Family Members
Journal of Molecular Biology·2011· 50 cited
Molecular coupling of Tsix regulation and pluripotency
Nature·2010· 206 cited
LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation
Cell·2010· 325 citedOpen Access
2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association
PLoS Biology·2010· 229 citedOpen Access
Nap1l2 Promotes Histone Acetylation Activity during Neuronal Differentiation
Molecular and Cellular Biology·2007· 64 citedOpen Access
<i>Tsix</i>-mediated epigenetic switch of a CTCF-flanked region of the <i>Xist</i> promoter determines the <i>Xist</i> transcription program
Genes & Development·2006· 134 citedOpen Access
Molecular cytogenetic characterization of the mouse cell line WMP2 by spectral karyotyping and multicolor banding applying murine probes
International Journal of Molecular Medicine·2006· 8 citedOpen Access
Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation
Nature Cell Biology·2006· 321 cited
<i>Tsix</i> transcription across the <i>Xist</i> gene alters chromatin conformation without affecting <i>Xist</i> transcription: implications for X-chromosome inactivation
Genes & Development·2005· 177 citedOpen Access
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts
Development·2005· 403 cited
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Frequent Co-authors

Édith Heard(10), Claire Rougeulle(6), Andrea Cerase(6), Ute C. Rogner(5), Danielle Arnaud(4), Constance Ciaudo(4), Mikaël Attia(3), Alexandros Armaos(3), Gian Gaetano Tartaglia(3), Laurence Amar(3), Christophe Rachez(3), Jennifer Chow(2), Melissa Fazzari(2), Nathan Mise(2), Nicolas Servant(2), Jacob L. Glass(2), Matthew Attreed(2), Anton Wutz(2), Emmanuel Barillot(2), John M. Greally(2)