Marjorie F. Lou

University of Nebraska–Lincoln — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index5.1kcitations162works2.72yr avg
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Research Topics

Connexins and lens biology(95), Redox biology and oxidative stress(57), Biochemical effects in animals(33), Sulfur Compounds in Biology(30), Aldose Reductase and Taurine(27)

Publications161 total

Optimizing cooling, power, freshwater, and hydrogen production in a dual-fuel gas turbine cycle: A multi-layered approach of waste heat recovery with biomass and methane integration
Renewable Energy·2025· 1 cited
Oxidation-Induced Mixed Disulfide and Cataract Formation: A Review
Antioxidants·2025· 7 citedOpen Access
A ternary reaction triggering fluorescence/colorimetric dual-mode signals for visual detection of ammonium nitrogen in environmental samples
SSRN Electronic Journal·2025Open Access
Glutathione and Glutaredoxin in Redox Regulation and Cell Signaling of the Lens
Antioxidants·2022· 64 citedOpen Access
Establishment of Thioltransferase knockout mouse model and the function of thioltransferase in cataractogenesis
SHILAP Revista de lepidopterología·2020· 1 citedOpen Access
Failure of Oxysterols Such as Lanosterol to Restore Lens Clarity from Cataracts
Scientific Reports·2019· 56 citedOpen Access
Does oxidative stress play any role in diabetic cataract formation? ----Re-evaluation using a thioltransferase gene knockout mouse model
Experimental Eye Research·2017· 27 cited
In vitro lens culture is a potent research tool for assessing chemical toxicity
2015
Expression and distribution of thiol-regulating enzyme glutaredoxin 2 (GRX2) in porcine ocular tissues
Experimental Eye Research·2014· 17 citedOpen Access
Glutaredoxin 2 (Grx2) Gene Deletion Induces Early Onset of Age-dependent Cataracts in Mice
Journal of Biological Chemistry·2014· 56 citedOpen Access
Glutaredoxin-2 Is Required to Control Oxidative Phosphorylation in Cardiac Muscle by Mediating Deglutathionylation Reactions
Journal of Biological Chemistry·2014· 97 citedOpen Access
Age-dependent Biochemical Changes in the Retina of Glutaredoxin 2 (Grx2) Knockout Mice
Investigative Ophthalmology & Visual Science·2013
Glutaredoxin-2 Is Required to Control Proton Leak through Uncoupling Protein-3
Journal of Biological Chemistry·2013· 65 citedOpen Access
Overexpression of thioredoxin-binding protein 2increases oxidation sensitivity and apoptosis in human lens epithelialcells
Free Radical Biology and Medicine·2013· 28 citedOpen Access
Ultraviolet Radiation–Induced Cataract in Mice: The Effect of Age and the Potential Biochemical Mechanism
Investigative Ophthalmology & Visual Science·2012· 59 citedOpen Access
Methyltransferase domain of human euchromatic histone methyltransferase 1, mutant Y1211A
2012
Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation
Experimental Eye Research·2012· 41 citedOpen Access
Thioredoxin 1 stimulates proliferation of human lens epithelial cells by activating NF-B pathway
Investigative Ophthalmology & Visual Science·2012
Glutaredoxin (Grx2) Gene Knockout Suppresses Fiber Cell Differentiation and Delays De-nucleation of the Mouse Lens
Investigative Ophthalmology & Visual Science·2012· 3 cited
Biochemical Changes in the Lenses of Glutaredoxin 2 Gene Knockout (KO) Mice
Investigative Ophthalmology & Visual Science·2012
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Frequent Co-authors

Jaime E. Dickerson(6), Kuiyi Xing(5), Vadim N. Gladyshev(4), M. Rohan Fernando(4), Frank J. Giblin(3), Wen-Ya Qiu(3), Hongli Wu(3), Douglas Borchman(3), Stefan Löfgren(3), Vanita A. Padgaonkar(2), Victor R. Leverenz(2), Li-Ren Lin(2), Nalin J. Unakar(2), Loan Dang(2), Venkat N. Reddy(2), Rekha Garadi(2), Qing Pan(2), Yufeng Yao(2), Ryan J. Mailloux(2), Jian Ying Xuan(2)