S Freestone

Charles River Laboratories (United Kingdom) — United Kingdom

Medicine · Health Sciences

21h-index1.5kcitations71works0.02yr avg
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Research Topics

Pharmacology and Obesity Treatment(7), Blood Pressure and Hypertension Studies(6), Pharmacological Effects and Toxicity Studies(6), Pharmacogenetics and Drug Metabolism(5), Hormonal Regulation and Hypertension(5)

Publications71 total

Absorption, metabolism, and excretion of <sup>14</sup>C gimatecan (LBQ707) after oral administration in patients with advanced cancer
Journal of Clinical Oncology·2007· 3 cited
Gonadotropin-Releasing Hormone Functionally Antagonizes Testosterone Activation of the Human Androgen Receptor in Prostate Cells through Focal Adhesion Complexes Involving Hic-5
Neuroendocrinology·2006· 31 cited
Differential Effects of Transforming Growth Factor-β1 on Cellular Proliferation in the Developing Prostate
Endocrinology·2004· 41 citedOpen Access
Gonadotropin-releasing Hormone-induced Activation of Diacylglycerol Kinase-ζ and Its Association with Active c-Src
Journal of Biological Chemistry·2004· 47 citedOpen Access
Sonic hedgehog regulates prostatic growth and epithelial differentiation
Developmental Biology·2003· 146 cited
A Randomized, Placebo‐Controlled, Crossover, Ascending Dose Tolerance and Pharmacokinetic Study of CVT‐3146: A Novel Agent For Potential Use in Myocardial Perfusion Imaging
Clinical Pharmacology & Therapeutics·2003· 5 citedOpen Access
Frovatriptan: A Review of Drug‐Drug Interactions
Headache The Journal of Head and Face Pain·2002· 48 cited
Lack of clinically significant interactions between frovatriptan and ergotamine, propranolol, or moclobemide
2001
Pharmacokinetics and tolerability of a novel 5-HT1D agonist, PNU-142633F.
PubMed·1999· 18 cited
Efficacy of CS-747, a new potent antiplatelet agent
Clinical Pharmacology & Therapeutics·1999· 2 cited
Candidate genes in complete and partial XY sex reversal: Mutation analysis of SRY, SRY-related genes and FTZ-F1
Molecular and Cellular Endocrinology·1998· 27 cited
A comparison of the pharmacokinetics of meropenem after intravenous administration by injection over 2, 3 and 5 minutes
European Journal of Drug Metabolism and Pharmacokinetics·1997· 12 cited
Hyponatraemia at a rave
Postgraduate Medical Journal·1997· 22 citedOpen Access
Effects of frusemide on the urinary excretion of dopamine and 5‐hydroxytryptamine in normal man
British Journal of Clinical Pharmacology·1996· 1 citedOpen Access
Effects of frusemide on the urinary excretion of dopamine and 5-hydroxytryptamine in normal man
British Journal of Clinical Pharmacology·1996· 1 citedOpen Access
γ‐l‐glutamyl‐5‐hydroxy‐l‐tryptophan, but not γ‐l‐glutamyl‐l‐tryptophan, causes sodium retention in normal man
British Journal of Clinical Pharmacology·1996· 2 citedOpen Access
Renal Metabolism and Effects of the Glutamyl Derivatives of <scp>l</scp>-Dopa and 5-Hydroxytryptophan in Man
Clinical Science·1996· 8 cited
Pressor effect of metoclopramide in phaeochromocytoma
Postgraduate Medical Journal·1996· 5 citedOpen Access
Blood and urine 5‐hydroxytryptophan and 5‐hydroxytryptamine levels after administration of two 5‐hydroxytryptamine precursors in normal man.
British Journal of Clinical Pharmacology·1995· 15 citedOpen Access
Effect of coffee and cigarette smoking on the blood pressure of patients with accelerated (malignant) hypertension.
PubMed·1995· 24 cited
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Frequent Co-authors

LE Ramsay(8), J H Silas(6), RF Jeffrey(6), MS Lennard(5), Thomas M. MacDonald(5), L. F. Prescott(5), Lawrence E. Ramsay(5), M. R. Lee(5), L E Ramsay(4), JH Silas(4), R. R. Samson(4), Geoffrey T. Tucker(3), Axel A. Thomson(3), J. A. N. McAuslane(3), T. C. Li Kam Wa(3), O. Cathal Grace(2), Darren C. Tomlinson(2), PR Jackson(2), GT Tucker(2), HF Woods(2)