Stewart Leung

HEC Pharm (China) — China

Medicine · Health Sciences

30h-index4.4kcitations40works0.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(22), interferon and immune responses(10), NF-κB Signaling Pathways(8), T-cell and B-cell Immunology(6), Immune Cell Function and Interaction(5)

Publications40 total

Time-Frequency DomainVoltage Feature Approach to Phase Identification using Smart Meter Data
2025
Abstract 6087: A novel Ly6G6D/4-1BB bispecific antibody targeting DNA mismatch repair proficient colorectal cancers shows potent antitumor activities
Cancer Research·2025
Preclinical characterization and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cell acute lymphoblastic leukemia: targeted immunotherapy for acute lymphoblastic leukemia
Frontiers of Medicine·2021· 17 cited
Central Review of Contours and Treatment Plans for Hemithoracic Intensity-Modulated Pleural Radiation Therapy (IMPRINT) – Implementation and Lessons Learned from a Prospective Multicenter Phase II Study
International Journal of Radiation Oncology*Biology*Physics·2019
From RORγt Agonist to Two Types of RORγt Inverse Agonists
ACS Medicinal Chemistry Letters·2018· 30 citedOpen Access
Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent RORγt inverse agonists
Bioorganic & Medicinal Chemistry·2015· 32 citedOpen Access
Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors
ACS Medicinal Chemistry Letters·2015· 76 citedOpen Access
Discovery of novel N-(5-(arylcarbonyl)thiazol-2-yl)amides and N-(5-(arylcarbonyl)thiophen-2-yl)amides as potent RORγt inhibitors
Bioorganic & Medicinal Chemistry·2013· 68 citedOpen Access
Retraction Note: Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease
Nature Medicine·2013Open Access
Discovery of Tertiary Amine and Indole Derivatives as Potent RORγt Inverse Agonists
ACS Medicinal Chemistry Letters·2013· 68 citedOpen Access
SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity
PLoS ONE·2012· 360 citedOpen Access
Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
Molecular Pharmacology·2012· 39 cited
Leukemia Inhibitory Factor Inhibits T Helper 17 Cell Differentiation and Confers Treatment Effects of Neural Progenitor Cell Therapy in Autoimmune Disease
Immunity·2011· 163 citedOpen Access
Interplay of Pathogenic TH1/TH17 Cells and Regulatory T Cells in Auto-immune Disease: A Tale of Yin and Yang
2011
The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease
Cellular and Molecular Immunology·2010· 238 citedOpen Access
Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease
Nature Medicine·2010· 132 cited
Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis
Journal of Neuroimmunology·2009· 179 citedOpen Access
Exploring mothers experiences in improving smoking hygiene at home: A qualitative study
2009
Differential Inhibition of Inducible T Cell Cytokine Secretion by Potent Iron Chelators
SLAS DISCOVERY·2005· 97 citedOpen Access
Interferon Signaling Is Dependent on Specific Tyrosines Located within the Intracellular Domain of IFNAR2c
Journal of Biological Chemistry·2002· 46 citedOpen Access
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Frequent Co-authors

George R. Stark(12), Yonghui Wang(6), Zhijun Xiang(6), Xiaoxia Li(5), Lei Fang(5), Neil G. Miyamoto(5), Ting Yang(5), Qianqian Wu(5), Jia‐Ning Xiang(5), Xichen Lin(5), Zhong Zhong(4), Ian M. Kerr(4), Xuebin Liu(4), Taylor B. Guo(4), Wei Cai(4), Guifeng Zhang(4), Ling Zhou(4), John D. Elliott(4), Yingli Ma(4), Lisa A. Orband‐Miller(4)