Astrid Pañeda

Abeona Therapeutics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.3kcitations39works0.02yr avg
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Research Topics

Virus-based gene therapy research(14), Plant pathogens and resistance mechanisms(12), Hepatitis B Virus Studies(6), RNA Interference and Gene Delivery(4), Viral gastroenteritis research and epidemiology(4)

Publications39 total

Updated results of Transpher A, a multicenter, single-dose, Phase 1/2 clinical trial of ABO-102 investigational gene therapy for Sanfilippo syndrome type A (mucopolysaccharidosis IIIA) (S39.008)
Neurology·2022· 5 cited
Interim results of Transpher A, a multicentre, single-dose, phase 1/2 clinical trial of ABO-102 investigational gene therapy for Sanfilippo syndrome type A (mucopolysaccharidosis IIIA)
Molecular Genetics and Metabolism·2022· 1 cited
Updated results of Transpher A: multicenter, single-dose, phase 1/2 clinical trial of ABO-102 for Sanfilippo syndrome type A (mucopolysaccharidosis IIIA)
Molecular Genetics and Metabolism·2021· 3 cited
Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria
Journal of Hepatology·2016· 139 citedOpen Access
O138 PHASE 1 CLINICAL TRIAL OF LIVER DIRECTED GENE THERAPY WITH rAAV5-PBGD IN ACUTE INTERMITTENT PORPHYRIA: PRELIMINARY SAFETY DATA
Journal of Hepatology·2014· 3 cited
Adeno-Associated Viral Vector Serotype 5 Poorly Transduces Liver in Rat Models
PLoS ONE·2013· 18 citedOpen Access
Safety and Liver Transduction Efficacy of rAAV5- <i>cohPBGD</i> in Nonhuman Primates: A Potential Therapy for Acute Intermittent Porphyria
Human Gene Therapy·2013· 60 citedOpen Access
Non-clinical safety evaluation of AAV5-PBGD in mice and cynomolgus macaques
Toxicology Letters·2013
137 TOXICOLOGY AND LIVER TRANSDUCTION EFFICACY EVALUATION OF A RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR IN NON HUMAN PRIMATES AS A POTENTIAL TREATMENT FOR ACUTE INTERMITTENT PORPHYRIA
Journal of Hepatology·2012
Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12
Journal of Virology·2011· 38 citedOpen Access
Development of a Liver-specific Tet-On Inducible System for AAV Vectors and Its Application in the Treatment of Liver Cancer
Molecular Therapy·2011· 58 citedOpen Access
Adeno-Associated Virus Liver Transduction Efficiency Measured by <i>in Vivo</i> [ <sup>18</sup> F]FHBG Positron Emission Tomography Imaging in Rodents and Nonhuman Primates
Human Gene Therapy·2011· 14 citedOpen Access
Molecular Therapy for Obesity and Diabetes Based on a Long-Term Increase in Hepatic Fatty-Acid Oxidation §Δ
Hepatology·2010· 136 citedOpen Access
Mapping and use of seed protein loci for marker-assisted selection of growth habit and photoperiod response in Nuña bean (Phaseolus vulgaris L.)
Euphytica·2010· 7 citedOpen Access
Mapping of QTLs for morpho-agronomic and seed quality traits in a RIL population of common bean (Phaseolus vulgaris L.)
Theoretical and Applied Genetics·2010· 123 citedOpen Access
Insulin-Like Growth Factor I Gene Transfer to Cirrhotic Liver Induces Fibrolysis and Reduces Fibrogenesis Leading to Cirrhosis Reversion in Rats
Hepatology·2009· 99 citedOpen Access
Effect of Adeno-Associated Virus Serotype and Genomic Structure on Liver Transduction and Biodistribution in Mice of Both Genders
Human Gene Therapy·2009· 107 cited
583 EVALUATION OF AAV-MEDIATED IFNa-GENE THERAPY EFFICACY IN HBV TRANSGENIC MICE: CONSTITUTIVE VERSUS INDUCIBLE EXPRESSION
Journal of Hepatology·2009Open Access
Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12
Journal of Virology·2008· 34 cited
PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector
Gene Therapy·2008· 18 cited
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Frequent Co-authors

Gloria González‐Aseguinolaza(20), Jesús Prìeto(18), Juan José Ferreira Fernández(11), Julien Crettaz(9), Antonio Fontanellas(8), Cristina Rodríguez‐Suárez(8), Laura Ochoa‐Callejero(8), Harald Petry(7), Ramón Giráldez(7), Pedro Berraondo(7), Alberto Benito(6), Ana Čampa(6), Cristina Olagüe(6), Itziar Otano(6), Esperanza López‐Franco(5), Stuart G. Beattie(5), Delia D’Avola(4), Juan Ruiz(4), Lucía Vanrell(4), Itsaso Mauleón(4)