Kelley F. Kitto

University of Minnesota — United States

Medicine · Health Sciences

24h-index2.5kcitations89works1.52yr avg
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Research Topics

Pain Mechanisms and Treatments(55), Neuropeptides and Animal Physiology(30), Neurotransmitter Receptor Influence on Behavior(18), Neuroscience and Neuropharmacology Research(13), Pharmacological Receptor Mechanisms and Effects(13)

Publications89 total

Spinal Mechanism of Strategically Substituted Agmatine (SSA3) (Abstract ID: 162662)
Journal of Pharmacology and Experimental Therapeutics·2025
Investigation of Non-Neuronal Cells in the Inhibitory Actions of the Neuromodulator Agmatine (Abstract ID: 162571)
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
Xylazine-Induced Tolerance and Interactions with Fentanyl (Abstract ID: 191759)
Journal of Pharmacology and Experimental Therapeutics·2025
HINT1 Inhibitors as Selective Modulators of MOR–NMDAR Cross-Regulation and Non-Opioid Analgesia
ACS Chemical Neuroscience·2025· 1 cited
Agmatine inhibits NMDA receptor–mediated calcium transients in mouse spinal cord dorsal horn via intact PSD95-nNOS signaling
Journal of Pharmacology and Experimental Therapeutics·2024· 2 citedOpen Access
Intrathecal or intravenous AAV9-IDUA/RGX-111 at minimal effective dose prevents cardiac, skeletal and neurologic manifestations of murine MPS I
Molecular Therapy — Methods & Clinical Development·2024· 1 citedOpen Access
HINT1 Inhibitors as Selective Modulators of MOR-NMDAR Cross Regulation and Non-Opioid Analgesia
2024· 1 citedOpen Access
Development of opioid analgesic tolerance in rat to extended-release buprenorphine formulated for laboratory subjects
PLoS ONE·2024· 2 citedOpen Access
Adeno-associated virus-mediated gene transfer of arginine decarboxylase to the central nervous system prevents opioid analgesic tolerance
Frontiers in Pain Research·2024· 3 citedOpen Access
Comparative dose effectiveness of intravenous and intrathecal AAV9.CB7.hIDS, RGX-121, in mucopolysaccharidosis type II mice
Molecular Therapy — Methods & Clinical Development·2024· 5 citedOpen Access
Biodistribution of Agmatine to Brain and Spinal Cord after Systemic Delivery
Journal of Pharmacology and Experimental Therapeutics·2023· 7 citedOpen Access
AAV-mediated gene transfer to colon-innervating primary afferent neurons
Frontiers in Pain Research·2023· 1 citedOpen Access
Analgesic and Side Effect Profiles of Novel Alpha-2 Adrenergic Receptor Agonists
Journal of Pharmacology and Experimental Therapeutics·2023Open Access
Long-term reversal of chronic pain behavior in rodents through elevation of spinal agmatine
Molecular Therapy·2023· 13 citedOpen Access
Strategically Substituted Agmatine Analogs Reduce Neuropathic Pain and Show Improved Pharmacokinetics Compared to Agmatine
The FASEB Journal·2022
Characterization of Novel, Agmatine‐Based NMDA Receptor Antagonists in Multiple Pain States
The FASEB Journal·2022
Targeting the somatosensory system with AAV9 and AAV2retro viral vectors
PLoS ONE·2022· 21 citedOpen Access
Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity
Journal of Pharmacology and Experimental Therapeutics·2021· 3 citedOpen Access
Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection
Molecular Pharmaceutics·2021· 8 citedOpen Access
Targeting the nociceptive somatosensory system with AAV9 and AAV2retro viral vectors
2021Open Access
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Frequent Co-authors

Carolyn A. Fairbanks(37), George L. Wilcox(26), Lucy Vulchanova(16), Maureen Riedl(14), Cristina D. Peterson(13), Laura S. Stone(9), R. Scott McIvor(9), Alice A. Larson(9), Daniel J. Schuster(8), Lalitha R. Belur(6), H. Oanh Nguyen(4), Kelly M. Podetz-Pedersen(4), Christopher N. Honda(4), Jaclyn A. Dykstra(3), Carrie L. Wade(3), Kelsey R. Pflepsen(3), Alexander G. J. Skorput(3), Brent M. Grocholski(2), Ivan J. Posthumus(2), Aaron C. Overland(2)