Bukeyan Miao

University of Michigan–Ann Arbor — United States

Chemical Engineering · Physical Sciences

18h-index1.5kcitations26works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Carbon dioxide utilization in catalysis(10), Protein Degradation and Inhibitors(8), Catalytic Alkyne Reactions(7), CO2 Reduction Techniques and Catalysts(7), Ubiquitin and proteasome pathways(6)

Publications26 total

Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer
Journal of Medicinal Chemistry·2023· 50 citedOpen Access
Discovery of SMD-3040 as a Potent and Selective SMARCA2 PROTAC Degrader with Strong <i>in vivo</i> Antitumor Activity
Journal of Medicinal Chemistry·2023· 47 citedOpen Access
Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer
Journal of Medicinal Chemistry·2023· 51 citedOpen Access
Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer
Journal of Medicinal Chemistry·2021· 134 citedOpen Access
Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer
Journal of Medicinal Chemistry·2021· 131 citedOpen Access
Abstract 1960: Targeted androgen receptor (AR) protein degradation for the treatment of metastatic castration-resistant prostate cancer (mCRPC)
Cancer Research·2020
Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands
Journal of Medicinal Chemistry·2019· 208 citedOpen Access
Intermediate Detection by SAESI‐MS/MS Unveiling the Catalytic Cycle in Negishi Coupling
Chinese Journal of Chemistry·2019· 2 cited
Negishi Coupling for Highly Selective Syntheses of Allenes via Ligand Effect and Mechanistic Study via SAESI‐MS/MS
Chinese Journal of Chemistry·2019· 14 cited
Direct Enantioselective and Regioselective Alkylation of β,γ-Unsaturated Carboxylic Acids with Chiral Lithium Amides as Traceless Auxiliaries
Organic Letters·2019· 29 cited
Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER)
Journal of Medicinal Chemistry·2019· 257 cited
Bis(cycloocta‐1,5‐diene)nickel‐Catalyzed Carbon Dioxide Fixation for the Stereoselective Synthesis of 3‐Alkylidene‐2‐indolinones
Advanced Synthesis & Catalysis·2017· 24 cited
CCDC 1465264: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
ChemInform Abstract: Cyclic anti‐Azacarboxylation of 2‐Alkynylanilines with Carbon Dioxide.
ChemInform·2016
Cyclic <i>Anti</i>-Azacarboxylation of 2-Alkynylanilines with Carbon Dioxide
Organic Letters·2016· 61 cited
ChemInform Abstract: The Renaissance of an Old Problem: Highly Regioselective Carboxylation of 2‐Alkynyl Bromides with Carbon Dioxide.
ChemInform·2016
The Renaissance of an Old Problem: Highly Regioselective Carboxylation of 2‐Alkynyl Bromides with Carbon Dioxide
Chemistry - A European Journal·2015· 25 cited
Zinc-mediated allylation of carbon dioxide—the LiOAc effect
Organic Chemistry Frontiers·2014· 22 cited
ChemInform Abstract: Direct Carboxylation of Allylic Halides with Carbon Dioxide in the Presence of Indium.
ChemInform·2014
Direct carboxylation of allylic halides with carbon dioxide in the presence of indium
Chemical Communications·2014· 36 cited
page 1 of 2Next →

Frequent Co-authors

Shengming Ma(15), Shaomeng Wang(8), Xin Han(6), Lijie Zhao(6), Weiguo Xiang(6), Chong Qin(6), Weiming Yuan(6), Mi Wang(5), Bo Wen(5), Duxin Sun(5), Suhua Li(5), Gen Li(5), Chao‐Yie Yang(4), Tianfeng Xu(4), Qiong Yu(4), Donna McEachern(4), Lu Wang(4), Weilong Lin(3), Tao Cao(3), Fan Wu(3)