Cheryl Zi Jin Phua

Memorial Sloan Kettering Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index866citations28works6.32yr avg
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Research Topics

Cancer Genomics and Diagnostics(6), Genetics, Aging, and Longevity in Model Organisms(5), Cancer Immunotherapy and Biomarkers(4), Ferroptosis and cancer prognosis(4), Fungal and yeast genetics research(3)

Publications28 total

Evolution of oncogene amplification across 86,000 cancer cell genomes
2026Open Access
431 | EZH2 GAIN‐OF‐FUNCTION MUTATIONS CONFER EVEROLIMUS SENSITIVITY IN DIFFUSE LARGE B CELL LYMPHOMA
Hematological Oncology·2025Open Access
p53-dependent crosstalk between DNA replication integrity and redox metabolism mediated through a NRF2-PARP1 axis
Nucleic Acids Research·2024· 11 citedOpen Access
PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression
Genome Medicine·2024· 13 citedOpen Access
A multimodal atlas of hepatocellular carcinoma reveals convergent evolutionary paths and ‘bad apple’ effect on clinical trajectory
Journal of Hepatology·2024· 14 citedOpen Access
Abstract 6123: Validating cancer modulated allostatic load as a composite biomarker for mortality in patients with cancer
Cancer Research·2024
Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma
Journal for ImmunoTherapy of Cancer·2023· 12 citedOpen Access
P-398 Elective Oocyte Cryopreservation – a viable alternative as a means of fertility preservation
Human Reproduction·2023Open Access
Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites, and pathways that regulate lifespan
GeroScience·2023· 9 citedOpen Access
Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities
Nature Communications·2023· 20 citedOpen Access
Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites and pathways that regulate lifespan
2023· 2 citedOpen Access
The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer
Research Square (Research Square)·2022Open Access
Trajectory of immune evasion and cancer progression in hepatocellular carcinoma
Nature Communications·2022· 56 citedOpen Access
Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast
eLife·2021· 31 citedOpen Access
Author response: Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast
2021Open Access
P69.05 Molecular and Cellular Heterogeneity Underpin Treatment Response Across a Spectrum of EGFR-Mutant Non-Small Cell Lung Cancer
Journal of Thoracic Oncology·2021Open Access
Author Correction: Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
Nature Communications·2021· 12 citedOpen Access
Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
Nature Communications·2021· 135 citedOpen Access
Evolution of Natural Lifespan Variation and Molecular Strategies of Extended Lifespan
2020· 1 citedOpen Access
Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
2020· 6 citedOpen Access
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Frequent Co-authors

Wai Leong Tam(12), Siming Ma(11), Weiwei Zhai(7), Jia Qi Lim(6), Tony Kiat Hon Lim(6), Han Chong Toh(6), Brian K. P. Goh(6), Pierce K. H. Chow(6), Hannah Lai(5), Wei Wan(5), Tracy Jiezhen Loh(5), Wei Qiang Leow(5), Yin Huei Pang(5), Peng Chung Cheow(5), Shridhar Ganpathi Iyer(5), Alfred Wei Chieh Kow(5), Yock Young Dan(5), Valerie Chew(5), Alaattin Kaya(5), Daniel Promislow(5)