Ivan S. F. Chan

The University of Texas Southwestern Medical Center — United States

Medicine · Health Sciences

35h-index5.8kcitations87works1.42yr avg
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Research Topics

Herpesvirus Infections and Treatments(34), Statistical Methods in Clinical Trials(26), Optimal Experimental Design Methods(13), Animal Virus Infections Studies(10), Poxvirus research and outbreaks(9)

Publications87 total

Abstract PS3-12-30: Targeting dendritic cells with CD40 agonist-based triplet immunotherapy induces IL12B-driven tumor control in triple-negative breast cancers
Clinical Cancer Research·2026
Abstract PS5-08-28: Phase I pilot of pegylated liposomal doxorubicin, CD40 agonist antibody CDX-1140, and Flt3 ligand CDX-301 in advanced HER2-negative breast cancer
Clinical Cancer Research·2026
Abstract B037: AB-2100, a PSMA-inducible CA9-specific CAR T cell product intended for the treatment of ccRCC provides long-term tumor responses in preclinical mouse model
Cancer Immunology Research·2024· 1 cited
A Generalized Rank-Based Inferential Seamless Phase 2/3 Design with Dose Selection
ICSA book series in statistics·2024· 1 cited
Abstract 38: AB-2100, a PSMA-inducible CA9-specific CAR T cell product for the treatment of ccRCC provides long-term tumor responses in preclinical mouse model
Cancer Research·2024
Accelerating drug development at Bristol Myers Squibb through innovation
Drug Discovery Today·2024· 7 cited
Development of AB-2100, an autologous integrated circuit T (ICT) cell therapy targeting CA9 intended for the treatment of ccRCC.
Journal of Clinical Oncology·2024· 1 cited
A rank-based approach to improve the efficiency of inferential seamless phase 2/3 clinical trials with dose optimization
Contemporary Clinical Trials·2023· 9 cited
381 Large-scale expansion and engineering of human NK cells sourced from peripheral blood versus umbilical cord blood
Regular and Young Investigator Award Abstracts·2022· 2 citedOpen Access
Abstract 6004: Surveying surface antigen expression in multiple myeloma preclinical models
Cancer Research·2022
A Simple Approach to Incorporating Historical Control Data in Clinical Trial Design and Analysis
Statistics in Biosciences·2022· 7 cited
Safety and efficacy of inactivated varicella zoster virus vaccine in immunocompromised patients with malignancies: a two-arm, randomised, double-blind, phase 3 trial
The Lancet Infectious Diseases·2019· 35 cited
Clinical Trials: Vaccine Development
2018
Inactivated varicella zoster vaccine in autologous haemopoietic stem-cell transplant recipients: an international, multicentre, randomised, double-blind, placebo-controlled trial
The Lancet·2018· 93 cited
Safety and immunogenicity of inactivated varicella-zoster virus vaccine in adults with hematologic malignancies receiving treatment with anti-CD20 monoclonal antibodies
Vaccine·2017· 42 cited
A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Clinical Trial to Study the Safety, Tolerability, Efficacy, and Immunogenicity of Inactivated Vzv Vaccine (ZVIN) in Recipients of Autologous Hematopoietic Cell Transplants (Auto-Hcts)
Biology of Blood and Marrow Transplantation·2017· 6 citedOpen Access
Review of Statistical Innovations in Trials Supporting Vaccine Clinical Development
Statistics in Biopharmaceutical Research·2016· 5 cited
A 9-Valent HPV Vaccine Against Infection and Intraepithelial Neoplasia in Women
Obstetrical & Gynecological Survey·2015· 42 cited
Reply to Dunning
The Journal of Infectious Diseases·2015
A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women
New England Journal of Medicine·2015· 1.4k citedOpen Access
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Frequent Co-authors

Myron J. Levin(14), Jeffrey L. Silber(12), Jon E. Stek(12), Janie Parrino(10), Paula W. Annunziato(9), Gary R. Johnson(8), Katia Schlienger(7), Kenneth E. Schmader(7), Michael N. Oxman(7), Jeffrey G. Smith(6), Michael J. Caulfield(6), Holly Matthews(5), Robert F. Betts(5), Christina Y. Chan(5), Vicki A. Morrison(5), Jane H. Zhang(5), Shu‐Chih Su(5), F. Schödel(5), Rupert Vessey(5), Jin Xu(5)